# US 10,441,702 B2 · Medical fluid temperature control

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- Number: US 10,441,702 B2
- Document ID: US10441702B2
- Status: Granted
- Kind: B2
- Application number: 15/284,792
- Filed: 2016-10-04
- Published: 2018-04-05
- Granted: 2019-10-15
- Earliest claimed: 2016-10-04
- Assignees: Fresenius Medical Care Holdings, Inc.
- Applicants: Fresenius Medical Care Holdings, Inc.
- Inventors: William Scott Crawford; Robert Matthew Ohline
- Web page: https://patentgrep.com/patent/US10441702B2

## CPC

- A61M 1/28: Peritoneal dialysis {; Other peritoneal treatment, e.g. oxygenation}
- A61M 1/1524: {the interface providing means for actuating on functional elements of the cassette, e.g. plungers}
- A61M 1/153: {the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas}
- A61M 1/154: {with sensing means or components thereof}
- A61M 1/155: {with treatment-fluid pumping means or components thereof}
- A61M 1/159: {specially adapted for peritoneal dialysis}
- A61M 1/1623: {Disposition or location of membranes relative to fluids}
- A61M 1/1629: {with integral heat exchanger}
- A61M 1/281: {Instillation other than by gravity}
- A61M 2205/127: with provisions for heating or cooling
- A61M 2205/3368: Temperature
- A61M 2205/3673: thermo-electric, e.g. Peltier effect, thermocouples, semi-conductors
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

Devices, systems, and methods can be used to deliver temperature-controlled medical fluids to patients. For example, this disclosure provides devices, systems, and methods for controlling the temperature of dialysate delivered to a patient during a peritoneal dialysis treatment.

## Claims

### Claim 1

A peritoneal dialysis machine comprising:
a console including a compartment configured to releasably receive a dialysis fluid cassette, the console including one or more thermoelectric modules arranged to be adjacent the cassette while the cassette is received by the compartment and to effectuate energy transfer with a dialysis fluid in a fluid flow path of the cassette that is adjacent the one or more thermoelectric modules;
a fluid temperature sensor arranged adjacent to the cassette while the cassette is received by the compartment, the fluid temperature sensor arranged near where the dialysis fluid exits the cassette to enter a patient line extending from the cassette and arranged to detect a temperature of the dialysis fluid after being affected by the one or more thermoelectric modules;
one or more processors coupled to the console and configured to control the one or more thermoelectric modules based on the temperature of the dialysis fluid detected by the fluid temperature sensor such that: (i) during a heating mode the one or more thermoelectric modules heat the dialysis fluid in the fluid flow path of the cassette and (ii) during a cooling mode the one or more thermoelectric modules cool the dialysis fluid in the fluid flow path of the cassette; and
an ambient temperature sensor arranged to detect an ambient temperature around the console,
wherein the one or more processors are configured to determine, based on the ambient temperature detected by the ambient temperature sensor, a target temperature for the dialysis fluid as measured by the fluid temperature sensor, and
wherein the target temperature is determined based on an anticipated change in the temperature of the dialysis fluid as the dialysis fluid flows from the peritoneal dialysis machine through the patient line to a patient receiving treatment from the peritoneal dialysis machine.

### Claim 2 (depends on 1)

The peritoneal dialysis machine of claim 1, wherein the one or more processors are configured to control the one or more thermoelectric modules based on the ambient temperature detected by the ambient temperature sensor.

### Claim 3 (depends on 1)

The peritoneal dialysis machine of claim 1, wherein the fluid temperature sensor is a first fluid temperature sensor, and wherein the peritoneal dialysis machine further comprises a second fluid temperature sensor located to detect the temperature of the dialysis fluid prior to being affected by the one or more thermoelectric modules.

### Claim 4 (depends on 3)

The peritoneal dialysis machine of claim 3,
wherein the one or more processors are configured to control the one or more thermoelectric modules based on the temperatures of the dialysis fluid detected by the first fluid temperature sensor and the second fluid temperature sensor.

### Claim 5 (depends on 1)

The peritoneal dialysis machine of claim 1, further comprising first and second movable piston heads, wherein the first and second movable piston heads are movable in a direction substantially perpendicular to the cassette.

### Claim 6 (depends on 1)

The peritoneal dialysis machine of claim 1, wherein the peritoneal dialysis machine is adapted to be connected to a supply of water and to a source of concentrate and to generate the dialysis fluid using the water and the concentrate.

### Claim 7 (depends on 1)

The peritoneal dialysis machine of claim 1, wherein the one or more processors are configured to control the one or more thermoelectric modules based on the target temperature.

### Claim 8 (depends on 1)

The peritoneal dialysis machine of claim 1, wherein the target temperature is determined to be greater than 37° C. based on the ambient temperature detected by the ambient temperature sensor being less than 37° C.

### Claim 9 (depends on 1)

The peritoneal dialysis machine of claim 1, wherein the target temperature is determined to be less than 37° C. based on the ambient temperature detected by the ambient temperature sensor being greater than 37° C.

### Claim 10 (depends on 1)

The peritoneal dialysis machine of claim 1, wherein the anticipated change in the temperature of the dialysis fluid as the dialysis fluid flows from the peritoneal dialysis machine through the patient line to the patient is determined based on a measured temperature of spent dialysate emptying from the patient in a drain line at a distance from the patient.

### Claim 11 (depends on 10)

The peritoneal dialysis machine of claim 10, wherein the distance from the patient is equal to a length of the patient line.
