# US 10,441,618 B2 · Moringa extract

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- Number: US 10,441,618 B2
- Document ID: US10441618B2
- Status: Granted
- Kind: B2
- Application number: 15/770,620
- Filed: 2016-10-21
- Published: 2018-11-08
- Granted: 2019-10-15
- Earliest claimed: 2015-10-28
- Assignees: Taiyo Kagaku Co., Ltd.
- Applicants: Kazuhiko Sugiura; Aditya Kulkarni
- Inventors: Kazuhiko Sugiura; Aditya Kulkarni
- Web page: https://patentgrep.com/patent/US10441618B2

## CPC

- A61K 36/185: Magnoliopsida (dicotyledons)
- A23F 5/465: {Flavouring with flavours other than natural coffee flavour or coffee oil}
- A23G 1/48: containing plants or parts thereof, e.g. fruits, seeds or extracts (containing gums A23G1/40)
- A23G 3/34: Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G 3/36: characterised by the composition {containing organic or inorganic compounds}
- A23G 3/48: containing plants or parts thereof, e.g. fruits, seeds, extracts (containing gums A23G3/42)
- A23G 4/00: Chewing gum
- A23G 4/068: {containing plants or parts thereof, e.g. fruits, seeds, extracts (containing gums A23G4/10)}
- A23G 9/42: containing plants or parts thereof, e.g. fruits, seeds, extracts (containing gums A23G9/34)
- A23L 2/52: Adding ingredients (adding preservatives A23B70/10)
- A23L 2/54: Mixing with gases
- A23L 9/10: Puddings; Dry powder puddings
- A23L 9/12: {Ready-to-eat liquid or semi-liquid desserts, e.g. puddings, not to be mixed with liquids, e.g. water, milk}
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A61K 31/7034: attached to a carbocyclic compound, e.g. phloridzin
- A61P 3/00: Drugs for disorders of the metabolism (of the blood or the extracellular fluid A61P7/00)
- A61P 3/02: Nutrients, e.g. vitamins, minerals
- A61P 3/04: Anorexiants; Antiobesity agents
- A61P 3/06: Antihyperlipidemics
- A61P 3/10: for hyperglycaemia, e.g. antidiabetics
- A61P 9/10: for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A61P 9/12: Antihypertensives
- A61P 27/02: Ophthalmic agents
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A23L 2/39: Dry compositions
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A61K 2236/331: using water, e.g. cold water, infusion, tea, steam distillation or decoction
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23F: COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23G: COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

A moringa extract containing a benzyl glucosinolate in a content of 6% by mass or more, calculated as a dry solid content of the extract, wherein the extract does not substantially contain an alkaloid. The moringa extract of the present invention for solving a first aspect is useful in the field of foodstuff or the like. Also, the PPAR activator of the present invention for solving a second aspect has excellent PPAR activation action, and has no disadvantages in side effects, so that it can be ingested for long term, which can be preferably used in foodstuff and the like. Therefore, the PPAR activator of the present invention for solving a second aspect can be expected to be used as a food, a supplement or a medicament not only for prevention of disease such as insulin resistance, hyperinsulinism, Type 2 diabetes, hypertension, hyperlipidemia, arterial sclerosis and obesity, but also for fatigue recovery or endurance improvement by improving basal metabolism. In addition, a benzyl glucosinolate-containing composition for solving a third aspect is useful in the field of foodstuff or the like.

## Claims

### Claim 1

A moringa extract comprising a benzyl glucosinolate in a content of 6% by mass or more, calculated as a dry solid content of the extract, wherein the extract does not substantially comprise an alkaloid.

### Claim 2 (depends on 1)

The moringa extract according to claim 1, wherein an extraction solvent of the extract is water.

### Claim 3 (depends on 1)

A benzyl glucosinolate-containing composition comprising a moringa extract as defined in claim 1 and an excipient.

### Claim 4 (depends on 1)

Foodstuff comprising a moringa extract as defined in claim 1, wherein the foodstuff is selected from the group consisting of beverages; concentrated original liquids or powders for preparing these beverages; cold confectioneries; noodles; confectioneries; a marine or livestock processed food; a dairy product; a fat or oil and a fat or oil processed food; a seasoning; a soup, a stew, a salad, a ready-made side dish and a pickle; health and nutritional supplemental foods; supplements; oral cavity refreshing agents; and foodstuff for a pet.