# US 10,441,552 B2 · Anti-microbial composition comprising cannabinoids

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- Number: US 10,441,552 B2
- Document ID: US10441552B2
- Status: Granted
- Kind: B2
- Application number: 16/293,136
- Filed: 2019-03-05
- Published: 2019-07-11
- Granted: 2019-10-15
- Earliest claimed: 2015-06-23
- Assignees: Axim Biotechnologies, Inc.
- Applicants: Axim Biotechnologies, Inc.
- Inventors: George E. Anastassov; Lekhram Changoer; Philippus Anne Van Damme
- Web page: https://patentgrep.com/patent/US10441552B2

## CPC

- A61K 31/05: Phenols {(cannabinoids A61K31/658)}
- A61K 31/658: {o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol}
- A01N 31/16: with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61K 9/06: Ointments; Bases therefor; {Other semi-solid forms, e.g. creams, sticks, gels (composition of ointments, creams or gels A61K47/00)}
- A61K 9/12: Aerosols; Foams {(A61K9/0043, A61K9/0056, A61K9/006, A61K9/0073 take precedence; spray-films A61K9/7015)}
- A61K 9/122: {Foams; Dry foams (edible foams A61K9/0056)}
- A61K 47/10: Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A61L 2/18: Liquid substances
- A61L 2103/05: Living organisms or biological materials
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

This invention discloses anti-bacterial and anti-fungal compositions in spray form, in cream form, in liquid form, and in powder form. The anti-bacterial and anti-fungal compositions comprise cannabinoids, specifically cannabidiol, cannabigerol, tetrahydrocannabinol, tetracannabidivarin, and/or cannabidivarin for anti-bacterial and anti-fungal activities. The anti-bacterial and anti-fungal compositions may be used to treat toe nail fungus, MRSA infection, herpes virus infection, tinea pedis, burn wound infections, sun burns, diabetic infections, eczema, impetigo, dermatophytosis, psoriasis, itchy skin, atopic dermatitis, dandruff, and general topical infections.

## Claims

### Claim 1

An anti-microbial powder for use on skin comprising:
cannabigerol at 2% to 10% by weight of the total composition;
butylhydroxytoluene as a preservative at 0.2% to 1.5% by weight of the total composition;
dimethylpolysiloxane as an emollient at 3% to 20% by weight of the total composition; and
a powder comprising talc and hydrated silica at 30% to 90% by weight of the total composition.

### Claim 2 (depends on 1)

The anti-microbial powder for use on skin of claim 1, further comprising ethanol at 5% to 30% by weight of the total composition.

### Claim 3 (depends on 2)

The anti-microbial powder for use on skin of claim 2, further comprising dimethyl ether as a propellant solvent at 20% to 70% by weight of the total composition.

### Claim 4 (depends on 3)

The anti-microbial power for use on skin of claim 3, wherein the powder is packaged in an aerosol can.

### Claim 5 (depends on 3)

The anti-microbial power for use on skin of claim 3, further comprising a fragrance.

### Claim 6 (depends on 5)

The anti-microbial power for use on skin of claim 5, wherein the powder is packaged in an aerosol can.

### Claim 7

An anti-microbial powder for use on skin comprising:
cannabigerol at 2% to 10% by weight of the total composition;
butylhydroxytoluene as a preservative at 0.2% to 1.5% by weight of the total composition;
dimethylpolysiloxane as an emollient at 3% to 20% by weight of the total composition;
a powder comprising talc and hydrated silica at 30% to 90% by weight of the total composition; and
dimethyl ether as a propellant solvent at 20% to 70% by weight of the total composition,
wherein the powder is packaged in an aerosol can.

### Claim 8 (depends on 7)

The anti-microbial power for use on skin of claim 7, further comprising a fragrance.