# US 10,441,522 B2 · Surfactant-containing cleaning agent compositions with specific combinations of four preservatives > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,441,522 B2 - Document ID: US10441522B2 - Status: Granted - Kind: B2 - Application number: 15/372,145 - Filed: 2016-12-07 - Published: 2017-06-15 - Granted: 2019-10-15 - Earliest claimed: 2015-12-11 - Assignees: Henkel AG & Co. KGaA - Applicants: Henkel AG & Co. KGaA - Inventors: Heike Schelges; Rainer Simmering; Barbara Heide; Melanie Rauschenberg - Web page: https://patentgrep.com/patent/US10441522B2 ## CPC - A61K 8/4953: {containing pyrimidine ring derivatives, e.g. minoxidil} - A61K 8/23: Sulfur; Selenium; Tellurium; Compounds thereof - A61K 8/34: Alcohols - A61K 8/347: {Phenols} - A61K 8/36: Carboxylic acids; Salts or anhydrides thereof - A61K 8/361: {Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof} - A61K 8/42: Amides - A61K 8/44: Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof - A61K 8/442: {substituted by amido group(s)} - A61K 8/463: {containing sulfuric acid derivatives, e.g. sodium lauryl sulfate} - A61K 8/4926: {having six membered rings} - A61K 8/602: {Glycosides, e.g. rutin} - A61Q 5/02: Preparations for cleaning the hair - A61Q 19/10: Washing or bathing preparations - A61K 2800/524: Preservatives - A61K 2800/592: Mixtures of compounds complementing their respective functions - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract Cleaning compositions include at least one specific preservative combination. The cleaning compositions are used for cleaning and/or caring for the skin and/or hair, and the specific preservative combination is used for the preservation of surfactant-containing cleaning compositions. ## Claims ### Claim 1 A cleaning composition, including, in a cosmetically acceptable carrier, a) at least one surfactant selected from the group consisting of anionic surfactants, cationic surfactants, amphoteric surfactants, non-ionic surfactants, and mixtures thereof, and b) at least one preservative mixture, selected from the group consisting of phenoxyisopropanol and formic acid, sulfite(s) and hexetidine, ethyl lauroyl arginate and formic acid, ethyl lauroyl arginate and chloroxylenol, hexetidine and benzyl alcohol, hexetidine and chloroxylenol, hexetidine and formic acid, and mixtures thereof, and c) further including at least two further preservatives, each selected from the group consisting of benzyl alcohol(s), undecylenic acid, formic acid, piroctone olamine, sulfite(s), hexetidine, ethyl lauroyl arginate, and chlorphenesin, with the provision that the cleaning composition includes at least 4 different preservatives. ### Claim 2 (depends on 1) The cleaning composition according to claim 1, wherein the at least one surfactant is included at a concentration of 0.5 to 60% by weight, based on the total weight of the cleaning composition. ### Claim 3 (depends on 1) The cleaning composition according to claim 1, wherein the at least one surfactant includes at least one anionic surfactant selected from the group consisting of (i) alkyl(ether) sulfate having 8 to 18 carbon atoms in the alkyl chain and 1 to 6 ethylene oxide units, (ii) C12-C18 alkylether carboxylates, (iii) C12-C18 acyl isethionates, (iv) C12-C18 acyl sarcosinates, (v) C12-C18 acyl taurines, and (vi) mixtures thereof. ### Claim 4 (depends on 1) The cleaning composition according to claim 1, wherein the at least one surfactant includes at least one cationic surfactant selected from the group consisting of (i) quaternized carboxylic acid triethanolamine ester salts, (ii) quaternized salts of carboxylic acids with diethanol alkylamines, (iii) quaternized salts of carboxylic acids with 1,2-dihydroxypropyldialkylamines, (iv) Quaternium-92, (v) C10-C22 alkyltrimethylammonium chlorides, and (vi) mixtures thereof. ### Claim 5 (depends on 1) The cleaning compositions according to claim 1, wherein the at least one surfactant includes at least one amphoteric surfactant selected from the group consisting of (i) C10-C18 alkyl betaines, (ii) C8-12-alkylamido(C1-4)-alkyl betaines, (iii) C10-C18 alkyl sulfobetaines, (iv) C10-C18 alkyl amphoacetates and amphodiacetates, (v) C10-C18 alkylamphopropionates and dipropionates, and (vi) mixtures thereof. ### Claim 6 (depends on 1) The cleaning composition according to claim 1, wherein the at least one surfactant includes at least one non-ionic surfactant selected from the group consisting of (i) C10-C18 alkyl polyglucosides, (ii) sorbitan esters and sorbitan ether esters, (iii) C10-C18 carboxylic acid monoethanol amides, (iv) C10-C18 alcohol ethoxylates with 2 to 40 mol ethylene oxide and/or propylene oxide per mol of alcohol, (v) C10-C18 amine oxides, (vi) glyceryl cocoates with 2 to 40 mol ethylene oxide and/or propylene oxide per mol of glyceryl cocoate, and (vii) mixtures thereof. ### Claim 7 (depends on 1) The cleaning composition according to claim 1, wherein the at least one preservative combination b) is included at a concentration of 0.001 to 10% by weight based on the total weight of the cleaning composition. ### Claim 8 (depends on 1) The cleaning composition according to claim 1, wherein a ratio by weight of the first preservative to the second preservative in the preservative mixture b) is from 10:1 to 1:10. ### Claim 9 (depends on 1) The cleaning composition according to claim 1, further including at least three further preservatives, each selected from the group consisting of benzyl alcohol(s), chloroxylenol, phenoxyisopropanol, undecylenic acid, formic acid, piroctone olamine, sulfite(s), hexetidine, ethyl lauroyl arginate, and chlorphenesin, with the provision that the cleaning composition includes at least 5 different preservatives. ### Claim 10 (depends on 1) The cleaning composition according to claim 1, further including at least four further preservatives, each selected from the group consisting of benzyl alcohol(s), chloroxylenol, phenoxyisopropanol, undecylenic acid, formic acid, piroctone olamine, sulfite(s), hexetidine, ethyl lauroyl arginate, and chlorphenesin, with the provision that the cleaning composition includes at least 6 different preservatives. ### Claim 11 (depends on 1) The cleaning composition according to claim 1, further including at least six further preservatives, each selected from the group consisting of benzyl alcohol(s), chloroxylenol, phenoxyisopropanol, undecylenic acid, formic acid, piroctone olamine, sulfite(s), hexetidine, ethyl lauroyl arginate, and chlorphenesin, with the provision that the cleaning composition includes at least 8 different preservatives. ### Claim 12 (depends on 1) The cleaning composition according to claim 1, wherein the at least two additional preservatives are is included at a concentration of 0.1 to 10% by weight relative to the total weight of the cleaning composition. ### Claim 13 A method for preservation of surfactant-containing cleaning compositions, including a) providing at least one preservative mixture in the cleaning composition, the at least one preservative mixture being selected from the group consisting of phenoxyisopropanol and formic acid, sulfite(s) and hexetidine, ethyl lauroyl arginate and formic acid, ethyl lauroyl arginate and chloroxylenol, hexetidine and benzyl alcohol, hexetidine and chloroxylenol, hexetidine and formic acid, and mixtures thereof, b) further including at least two further preservatives, each selected from the group consisting of benzyl alcohol(s), undecylenic acid, formic acid, piroctone olamine, sulfite(s), hexetidine, ethyl lauroyl arginate, and chlorphenesin, with the provision that the cleaning composition includes at least 4 different preservatives. ### Claim 14 A cleansing composition, in a cosmetically acceptable carrier, comprising at least one surfactant, selected from the group consisting of anionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants, and mixtures thereof, and a combination of preservatives consisting of: a first preservative mixture selected from the group consisting of phenoxyisopropanol and piroctone olamine, phenoxyisopropanol and formic acid, sulfite(s) and hexetidine, ethyl lauroyl arginate and formic acid, ethyl lauroyl arginate and chloroxylenol, hexetidine and benzyl alcohol, hexetidine and chloroxylenol, hexetidine and piroctone olamine, hexetidine and chlorophenesin, hexetidine and formic acid, and mixtures thereof and further including at least two further preservatives, each selected from the group consisting of benzyl alcohol(s), chloroxylenol, phenoxyisopropanol, undecylenic acid, formic acid, piroctone olamine, sulfite(s), hexetidine, ethyl lauroyl arginate, and chlorphenesin, with the provision that the cleaning composition includes at least 4 different preservatives.