# US 10,441,405 B2 · Orthotopic artificial bladder endoprosthesis > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,441,405 B2 - Document ID: US10441405B2 - Status: Granted - Kind: B2 - Application number: 15/515,043 - Filed: 2015-09-28 - Published: 2017-08-03 - Granted: 2019-10-15 - Earliest claimed: 2014-09-30 - Applicants: Antonio Sambusseti; Gianni Cancarini - Inventors: Antonio Sambusseti; Gianni Cancarini - Web page: https://patentgrep.com/patent/US10441405B2 ## CPC - A61F 2/042: {Urinary bladders} - A61F 2210/0004: bioabsorbable - A61F 2230/0071: spherical - A61F 2250/0003: having an inflatable pocket filled with fluid, e.g. liquid or gas - A61F 2250/0059: temporary - A61L 27/18: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds - A61L 27/303: {Carbon} - A61L 2430/22: for reconstruction of hollow organs, e.g. bladder, esophagus, urether, uterus - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) ## Abstract An orthotopic artificial bladder endoprosthesis includes a casing made of a PGA fiber fabric; the casing having two first connectors for the connection with the ureters of a patient and a further connector for the connection with the urethra of a patient; an inflatable element inserted in the casing; the inflatable element being switchable between an inflated configuration, in which it supports and maintains in position the casing, and a deflated configuration. ## Claims ### Claim 1 An orthotopic artificial bladder endoprosthesis for insertion into a patient configured to enable formation of a neobladder comprising: a casing made of a PGA fiber fabric configured to resorb over approximately one month; the casing having two first connectors for connection with the ureters of the patient and a second connector for connection with the urethra of the patient; and an inflatable element inserted in the casing and being independent of the casing; the inflatable element being switchable between an inflated configuration, in which the inflatable element is configured to support and maintain in position the casing the entire time necessary for the formation of a neobladder occurring at the same time as the progressive dissolution of the PGA casing in one month, and a deflated configuration, wherein the inflatable element comprises a membrane having an external surface, wherein the membrane of the inflatable element has an internal surface directed towards and defining an enclosure, wherein the inflatable element has a valve for introducing and extracting a fill fluid for expanding the inflatable element to the inflated configuration in which the inflatable element supports and maintains in position the casing, wherein the valve directly protrudes from the inflatable element, wherein the inflatable element defines the enclosure for the fill fluid, the valve being in direct communication with the enclosure, the valve adapted and configured to be within the casing when the inflatable element is in the inflated configuration, wherein in the inflated configuration the inflatable element extends across the casing to support opposed sides of the casing, wherein in the inflated configuration the inflatable element has a volume between 300 cm3 and 400 cm3 and the casing has a volume between 300 cm3 and 400 cm3. ### Claim 2 (depends on 1) The endoprosthesis according to claim 1, wherein the inflatable element has an external surface covered with turbostratic pyrolytic carbon. ### Claim 3 (depends on 1) The endoprosthesis according to claim 1, wherein the inflatable element has a spherical shape in the inflated configuration. ### Claim 4 (depends on 1) The endoprosthesis according to claim 1, wherein the inflatable element is constituted by a silicone membrane and the valve for introducing and extracting the fill fluid is directly protruding from the silicone membrane; wherein the inflatable element membrane and valve are within the casing. ### Claim 5 (depends on 4) The endoprosthesis according to claim 4, wherein the valve is independent of the first connectors and/or the second connector. ### Claim 6 (depends on 1) The endoprosthesis according to claim 1, wherein the inflatable element membrane is constituted by a multilayer silicone membrane. ### Claim 7 (depends on 1) The endoprosthesis according to claim 1, wherein in the inflated configuration the inflatable element volume is between 300 cm3 and 350 cm3 and the casing volume is between 300 cm3 and 400 cm3. ### Claim 8 (depends on 3) The endoprosthesis according to claim 3, wherein the valve is independent of the first connectors and the second connector. ### Claim 9 (depends on 1) The endoprosthesis according to claim 1, wherein the valve is independent of the first connectors and/or the second connector. ### Claim 10 (depends on 2) The endoprosthesis according to claim 2, wherein the inflatable element membrane is constituted by a multilayer silicone membrane. ### Claim 11 (depends on 3) The endoprosthesis according to claim 3, wherein the inflatable element membrane is constituted by a multilayer silicone membrane. ### Claim 12 (depends on 1) The endoprosthesis according to claim 1, wherein the PGA fabric of the casing has a thickness between 0.3 mm and 0.6 mm. ### Claim 13 (depends on 1) The endoprosthesis according to claim 1, wherein the PGA fabric of the casing has a thickness between 0.4 mm and 0.53 mm. ### Claim 14 (depends on 4) The endoprosthesis according to claim 4, wherein the inflatable element is completely detached from the casing. ### Claim 15 (depends on 1) The endoprosthesis according to claim 1, wherein the inflatable element valve for introducing and extracting the fill fluid is within the casing. ### Claim 16 (depends on 15) The endoprosthesis according to claim 15, wherein the inflatable element valve has opposed first and second ends, the first end attached to the inflatable element, the second end freely extending to be exposed to an interior cavity of the casing. ### Claim 17 An orthotopic artificial bladder endoprosthesis for insertion into a patient configured to enable formation of a neobladder comprising: a casing made of a PGA fiber fabric configured to resorb over approximately one month; the casing having two first connectors for connection with the ureters of the patient and a second connector for connection with the urethra of the patient; and an inflatable element inserted in the casing and being independent of the casing; the inflatable element being switchable between an inflated configuration, in which the inflatable element is configured to support and maintain in position the casing the entire time necessary for the formation of a neobladder occurring at the same time as the progressive dissolution of the PGA casing in one month, and a deflated configuration, wherein the inflatable element comprises a membrane having an external surface, wherein the membrane of the inflatable element has an internal surface directed towards and defining an enclosure, wherein the inflatable element has a valve for introducing and extracting a fill fluid for expanding the inflatable element to the inflated configuration in which the inflatable element supports and maintains in position the casing, wherein the valve directly protrudes from the inflatable element, wherein the inflatable element defines the enclosure for the fill fluid, the valve being in direct communication with the enclosure, the valve adapted and configured to be within the casing when the inflatable element is in the inflated configuration, wherein in the inflated configuration the inflatable element extends across the casing to support opposed sides of the casing, wherein the inflatable element valve for introducing and extracting the fill fluid is within the casing, wherein the inflatable element valve has opposed first and second ends, the first end attached to the inflatable element, the second end freely extending to be exposed to an interior cavity of the casing. ### Claim 18 (depends on 17) The endoprosthesis according to claim 17, wherein the inflatable element has an external surface covered with turbostratic pyrolytic carbon. ### Claim 19 (depends on 17) The endoprosthesis according to claim 17, wherein the inflatable element membrane is constituted by a multilayer silicone membrane.