# US 10,441,293 B2 · Hemostatic method > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,441,293 B2 - Document ID: US10441293B2 - Status: Granted - Kind: B2 - Application number: 15/401,388 - Filed: 2017-01-09 - Published: 2018-07-12 - Granted: 2019-10-15 - Earliest claimed: 2017-01-09 - Assignees: Southern Taiwan University of Science and Technology - Applicants: Southern Taiwan University of Science and Technology - Inventors: Yi-Chun Du; Bee-Yen Lim; Shi-han Chen - Web page: https://patentgrep.com/patent/US10441293B2 ## CPC - A61B 17/1325: {with means for applying local pressure (pressure pads A61F5/30)} - A61B 5/026: Measuring blood flow {(A61B3/1233, A61B3/1241 take precedence)} - A61B 5/02042: {Determining blood loss or bleeding, e.g. during a surgical procedure} - A61B 5/024: Measuring pulse rate or heart rate - A61B 5/0261: {using optical means, e.g. infrared light} - A61B 5/14542: {for measuring blood gases (A61B5/14551 takes precedence)} - A61B 5/4836: {Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence)} - A61B 17/135: inflatable - A61B 2017/00022: {Sensing or detecting at the treatment site} - A61B 2017/00106: {ultrasonic} - A61B 2017/00115: {with audible or visual output} - A61B 2017/00398: {using powered actuators, e.g. stepper motors, solenoids} - A61B 2017/00716: {simulating physical properties} - A61B 2505/05: Surgical care - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A hemostatic method is performed as follows: A) An at-puncture hemostatic pressure is applied to a puncture in a blood vessel via a main geometric side, and at least one off-puncture hemostatic pressure is applied to at least one position away from the puncture via at least one auxiliary geometric side, wherein the off-puncture hemostatic pressure acts on the blood vessel either directly or indirectly. B) During the hemostatic process, an ongoing flow velocity of the blood in the blood vessel is obtained and is reduced to lower than a normal flow velocity in the blood vessel by applying the at-puncture and off-puncture hemostatic pressures simultaneously, wherein the at-puncture and off-puncture hemostatic pressures are lower than a systolic pressure in the blood vessel. ## Claims ### Claim 1 A hemostatic method, comprising: A) providing a main hemostatic element having a main geometric side and at least one auxiliary hemostatic element having an auxiliary geometric side; B) performing a hemostatic process including (1) applying an at-puncture hemostatic pressure to a puncture in a blood vessel via the main geometric side of the main hemostatic element, and (2) applying at least one off-puncture hemostatic pressure to at least one position away from the puncture via the at least one auxiliary geometric side of the at least one auxiliary hemostatic element, wherein the at least one off-puncture hemostatic pressure acts on the blood vessel directly or indirectly; and C) obtaining an initial flow velocity in the blood vessel prior to performing the hemostatic process, obtaining an ongoing flow velocity of blood in the blood vessel during the hemostatic process, and rendering the ongoing flow velocity lower than the initial flow velocity in the blood vessel by applying the at-puncture hemostatic pressure and the at least one off-puncture hemostatic pressure simultaneously, wherein the at-puncture hemostatic pressure and the at least one off-puncture hemostatic pressure are lower than a systolic pressure in the blood vessel. ### Claim 2 (depends on 1) The hemostatic method of claim 1, wherein the step C includes rendering the ongoing flow velocity lower than 60% of the initial flow velocity. ### Claim 3 (depends on 1) The hemostatic method of claim 1, wherein said at least one auxiliary hemostatic element includes a plurality of auxiliary hemostatic elements each having a respective auxiliary geometric side, the main geometric side has a main geometric center, each said auxiliary geometric side has an auxiliary geometric center, and the auxiliary geometric centers are equidistantly spaced from the main geometric center. ### Claim 4 (depends on 3) The hemostatic method of claim 3, wherein each said auxiliary geometric center is 0.5 cm to 3.5 cm away from the main geometric center. ### Claim 5 (depends on 3) The hemostatic method of claim 3, wherein the main geometric side has a main geometric side periphery, each said auxiliary geometric side has an auxiliary geometric side periphery, and a shortest distance between the main geometric side periphery and the auxiliary geometric side peripheries is greater than 0 cm and smaller than 3.5 cm. ### Claim 6 (depends on 1) The hemostatic method of claim 1, wherein said at least one auxiliary hemostatic element includes a plurality of auxiliary hemostatic elements each having a respective auxiliary geometric side, the main geometric side has a main geometric center, each said auxiliary geometric side has an auxiliary geometric center, and the auxiliary geometric centers are non-equidistantly spaced from the main geometric center. ### Claim 7 (depends on 6) The hemostatic method of claim 6, wherein each said auxiliary geometric center is 0.5 cm to 3.5 cm away from the main geometric center. ### Claim 8 (depends on 6) The hemostatic method of claim 6, wherein the main geometric side has a main geometric side periphery, each said auxiliary geometric side has an auxiliary geometric side periphery, and a shortest distance between the main geometric side periphery and the auxiliary geometric side peripheries is greater than 0 cm and smaller than 3.5 cm. ### Claim 9 (depends on 1) The hemostatic method of claim 1, wherein the at least one off-puncture hemostatic pressure is equal to the at-puncture hemostatic pressure. ### Claim 10 (depends on 1) The hemostatic method of claim 1, wherein the step C includes obtaining a plurality of said ongoing flow velocities at different times respectively and changing the at-puncture hemostatic pressure and/or the at least one off-puncture hemostatic pressure during the hemostatic process according to each said ongoing flow velocity obtained. ### Claim 11 (depends on 1) The hemostatic method of claim 1, wherein the step C includes obtaining the ongoing flow velocity via an optical or ultrasonic measuring device. ### Claim 12 (depends on 1) The hemostatic method of claim 1, wherein the at-puncture hemostatic pressure and the at least one off-puncture hemostatic pressure are provided by operating a pressurizing device manually. ### Claim 13 (depends on 1) The hemostatic method of claim 1, wherein the at-puncture hemostatic pressure and the at least one off-puncture hemostatic pressure are provided by controlling a pressurizing device through a computer program. ### Claim 14 (depends on 1) The hemostatic method of claim 1, further comprising using a controller during the hemostatic process to gather one or more pieces of information selected from the group consisting of: the at-puncture hemostatic pressure, the at least one off-puncture hemostatic pressure, the ongoing flow velocity, the systolic pressure, a duration of hemostatic operation, a working temperature of the main geometric side, and a working temperature of the auxiliary geometric side. ### Claim 15 (depends on 14) The hemostatic method of claim 14, wherein the step of using a controller during the hemostatic process to gather one or more pieces of information further includes outputting the gathered information via the controller. ### Claim 16 (depends on 15) The hemostatic method of claim 15, wherein the step of using a controller during the hemostatic process to gather one or more pieces of information further includes comparing the gathered information with a predetermined value and selectively outputting a notification signal according to a comparison result.