# US 10,440,953 B2 · Control of pests in maize by ginkgolides and bilobalide

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- Number: US 10,440,953 B2
- Document ID: US10440953B2
- Status: Granted
- Kind: B2
- Application number: 15/749,823
- Filed: 2016-08-05
- Published: 2018-08-09
- Granted: 2019-10-15
- Earliest claimed: 2015-08-07
- Assignees: BASF SE
- Applicants: BASF SE
- Inventors: Birgit Gockel; Joachim Dickhaut; Daniel Saelinger
- Web page: https://patentgrep.com/patent/US10440953B2

## CPC

- A01N 43/90: having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS

## Abstract

Described herein is a method for controlling pests of a maize plant, including the step of contacting the maize plant, parts of the maize plant, or its propagation material with components of the ginkgo tree selected from bilobalide, ginkgolide A, ginkgolide B, ginkgolide C, ginkgolide J, ginkgolide M, and mixtures thereof. Further described herein is the use of the components of the ginkgo tree for controlling pests on the maize plant, parts of the maize plant, or its plant propagation material.

## Claims

### Claim 1

A method for controlling pests selected from the family of Pentatomidae, Thripidae, or a combination thereof of a genetically modified maize plant having at least one toxin of Bacillus thuringiensis formed in the plant, the method comprising contacting the maize plant, parts of the maize plant, or its propagation material with components of a ginkgo tree selected from the group consisting of bilobalide, ginkgolide A, ginkgolide B, ginkgolide C, ginkgolide J and ginkgolide M, and mixtures thereof:
wherein the genetically modified maize plant has at least one toxin of Bacillus thuringiensis formed in the plant;
wherein the pests are selected from the family of Pentatomidae, Thripidae, or a combination thereof; and
wherein said pests contact said components of a ginkgo tree.

### Claim 2 (depends on 1)

The method of claim 1, wherein the pests are from the family of Pentatomidae.

### Claim 3 (depends on 1)

The method of claim 1, wherein the pests are one of Euschistus spp., Halyomorpha spp., Dichelops spp., Nezara spp., and Oebalus spp.

### Claim 4 (depends on 1)

The method according to claim 1, wherein the pests are one of Euschistus servus, Euschistus heros, Halyomorpha halys, Dichelops furcatus, Dichelops melacanthus, Nezara viridula, and Oebalus pugnax.

### Claim 5 (depends on 1)

The method according to claim 1, further comprising applying the components of the ginkgo tree using a soil drench treatment.

### Claim 6 (depends on 1)

The method according to claim 1, further comprising applying the components of the ginkgo tree using an in-furrow treatment.

### Claim 7 (depends on 1)

The method according to claim 1, further comprising applying the components of the ginkgo tree using a foliar application.

### Claim 8 (depends on 1)

The method according to claim 1, further comprising applying the components of the ginkgo tree in an amount between about 1 g/Ha and about 500 g/ha.

### Claim 9 (depends on 1)

The method according to claim 1, wherein the components of the ginkgo tree are one of ginkgolide A, bilobalide, and a mixture thereof.

### Claim 10 (depends on 1)

The method according to claim 1, wherein the maize plant has been modified by mutagenesis or genetic engineering.

### Claim 11 (depends on 1)

The method according to claim 1, wherein the genetically modified maize plant has an insect resistance conveyed by a gene selected from the group consisting of cry1Aa, cry1Ab, cry1A.105, cry1F, cry1Fa2, cry2Ab2, cry2Ae, cry3Bb1, cry3Bb1, cry34Ab1, cry35Ab1, cry9c, dvsnf7, ecry3.1Ab, mcry3A, mocry1F, pint, vip3Aa20, and combinations thereof.

### Claim 12 (depends on 1)

The method according to claim 1, wherein the genetically modified maize plant has an insect resistance conveyed by a gene selected from the group consisting of cry3Bb1, cry34Ab1, cry35Ab1, ecry3.1Ab, mcry3A, and combinations thereof.

### Claim 13 (depends on 1)

The method according to claim 1, wherein the genetically modified maize plant has a herbicide tolerance conveyed by at least one gene selected from the group consisting of pat, mepsps, cp4 epsps, zm-hra, gat4621, aad1, bar, 2mepsps, gov247, epsps grg23ace5, ACCase (mutant), als (mutant), dmo, and combinations thereof.