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US 10,435,563 B2Granted
Water soluble fluorescent or colored dyes and methods for their use
AssigneesSony Corporation, Sony Corporation of America
InventorsTracy Matray, Hesham Sherif, C. Frederick Battrell
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Abstract
Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I): including stereoisomers, salts and tautomers thereof, wherein R1, R2, R3, L1, L2, L3, L4, L5, L6, M1, M2, A, q, w and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.
Claims20
A water soluble, oligomeric dye compound having the following structure:
- wherein:
- M1 is, at each occurrence, independently a moiety comprising three or more aryl or heteroaryl rings, or combinations thereof;
- L1, L2, and L3 are, at each occurrence, independently optional linkers comprising atoms selected from C, O, S, N and P;
- R1 is, at each occurrence, independently H, alkyl, or alkoxy;
- R2 and R3 are independently H, OH, SH, NH2, alkyl, alkylether, hydroxlalkyl, aminoalkyl, hydroxylalkylether, sulfhydrylalkyl, sulfyhdrylalkylether, phosphate, thiophosphate, alkylphospho, alkylthiophospho, —Oalkylphospho, —Oalkylthiophospho, alkyletherphospho, alkyletherthiophospho, —Oalkyletherphospho, —Oalkyletherthiophospho phosphoalkyl, phosphoalkylether, thiophosphoalkyl, thiophosphoalkylether, —Ophosphoalkyl, O-phosphoalkylether, —Othiophosphoalkyl or —Othiophosphoalkylether or a linker comprising a covalent bond to a biomolecule or microparticle;
- and
- n is an integer from 2 to 20.
4 more elements
Dependencies are inferred from the claim text.