Back to results
US 10,422,795 B2Granted
Urinary crystal detection method
AssigneeNational Yang-Ming University
InventorsHui-Hua Chiang, Chih-Chia Huang
Life of this patent
Estimating the term…
Abstract
The present invention provides an urinary crystal detection method, which is used with a crystal collecting unit and a crystal detecting unit. The method comprises steps of using magnetic particles to attach urinary crystals from a sample. Then, providing a magnetic field to separate the urinary crystals. Further to analyz their constituent by the Raman signals of the urinary crystal to access an urinary calculus result for urinary stone patient.
Claims12
An urinary crystal detection method, comprising steps:
- providing a urine sample from a patient;
- adding a plurality of magnetic particles into the urine sample, the magnetic particles attaching to a plurality of urine crystals of the urine sample, wherein the magnetic particles are formed as a core, which is coated with gelatin, and the surfaces of the magnetic particles are modified by PO(OH)2 or PO43− groups to attach the urinary crystals with Ca or Mg;
- providing a magnetic field to attract the magnetic particles by a magnetic separating device, and collecting the urinary crystals which are absorbed by the magnetic particles;
- analyzing a Raman signal of the urinary crystals by a microscopic Raman spectroscopy unit;
- comparing the peak characteristics of the Raman signal with a component information from a database, wherein the component information is a plurality of reference peak characteristics from different urinary crystals related to a plurality of urinary calculus;
- and
- receiving a result of the urinary calculus which the reference peak characteristics is similar as the Raman signal.
4 more elements
Dependencies are inferred from the claim text.