Feline calicivirus vaccine
AssigneeIntervet Inc.
InventorsErald Shehu, Amrut Shridhar Bhogle
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Abstract
The present invention relates to a new feline capsid protein, to live attenuated feline calicivirus comprising that capsid protein, to live recombinant carrier viruses and live attenuated hybrid feline calicivirus comprising that capsid protein, to vaccines comprising such live attenuated feline caliciviruses, live recombinant carrier viruses and live attenuated hybrid feline calicivirus, and to methods for the preparation of such viruses.
Claims19
A feline calicivirus (FCV) capsid protein comprising a sequence identity of at least 90% with the amino acid sequence of SEQ ID NO:
- 34.
A feline calicivirus (FCV) capsid protein comprising at least one of the following amino acids K89, M90, M100, I317, L390, A391, V392, Q396, S397, K398, N404, T426, T431, S438, S437, D440, E445, K447, L448, E451, N452, G484, G489, I491, N516, S517, E518, I524, S545, S634, F635, P636, wherein the numbering is according to SEQ ID NO:
- 34.
A live attenuated FCV comprising a capsid protein comprising a sequence identity of at least 90% with the amino acid sequence of SEQ ID NO:
- 34.
A live attenuated feline calicivirus (FCV) comprising a capsid protein wherein the capsid protein comprises at least one of the following amino acids K89, M90, M100, I317, L390, A391, V392, Q396, S397, K398, N404, T426, T431, S438, S437, D440, E445, K447, L448, E451, N452, G484, G489, I491, N516, S517, E518, I524, S545, S634, F635, P636.
Dependencies are inferred from the claim text.