Back to results
US 10,421,722 B2Granted
Sulfur-containing compounds targeting vesicular acetylcholine transporter
AssigneesWashington University, The Regents of the University of California
InventorsZhude Tu, Zonghua Luo, Hui Liu, Hongjun Jin, Stanley M. Parsons
Life of this patent
Estimating the term…
Abstract
The present invention generally relates to various compounds that are useful as vesicular acetylcholine transporter (VAChT) ligands. The invention further relates to methods of using these compounds and their radiolabeled analogs for the detection of neurodegenerative diseases including Parkinson's disease (PD), and Alzheimer's disease (AD).
Claims20
A compound having a structure of Formula I, or a salt thereof:
- wherein R1, R2, and R3 are each independently hydrogen, C1-C6 alkyl, or
- and at least one of R1, R2, and R3 is
- R4 is a substituted or unsubstituted C1-C6 alkyl;
- substituted or unsubstituted amino;
- m is 0, 1 or 2;
- and
- n is 0 or 1.
4 more elements
Dependencies are inferred from the claim text.