25-hydroxy vitamin D3 complex and methods of manufacture and its applications
AssigneeRcc Corporation Limited
InventorHaiyan Fan
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Abstract
This invention provides a 25-OH Vitamin D3 complex, this complex is made of β-cyclodextrin and/or its derivatives and 25-Hydroxy Vitamin D3. This invention also relates to a method of manufacturing this complex of β-cyclodextrin and 25-Hydroxy Vitamin D3, as well as its applications. Due to there being many hydroxy groups at the outside of β-cyclodextrin and/or its derivatives, the complex increases the solubility of entrapped 25-HO Vitamin D3, thus increasing its bioavailability greatly. In addition, the ring structure of β-cyclodextrin protects the unstable unsaturated double bonds of 25-HO Vitamin D3, shield it from oxygen and other harmful chemicals and make it much more stable.
Claims9
A 25-Hydroxy Vitamin D3 complex, characterized in that, it comprises β-cyclodextrin and 25-hydroxy Vitamin D3,
- wherein the complex includes 25-hydroxy Vitamin D3 molecules encapsulated within β-cyclodextrin molecules and wherein the mass ratio of β-cyclodextrin and 25-hydroxy Vitamin D3 is:
- 6:1 to 12:1.
Dependencies are inferred from the claim text.