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US 10,420,762 B2Granted
Pharmaceutical preparation containing oxycodone and naloxone
AssigneePurdue Pharma L.P.
InventorsBianca Brögmann, Silke Mühlau, Christof Spitzley
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Abstract
The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
Claims20
An oral pharmaceutical formulation comprising:
- about 40 mg to 150 mg of oxycodone or a pharmaceutically acceptable salt thereof;
- and naloxone or a pharmaceutically acceptable salt thereof;
- wherein the oxycodone or pharmaceutically acceptable salt thereof and the naloxone or pharmaceutically acceptable salt thereof are present in the pharmaceutical formulation in a weight ratio of 2:1 and are released from the pharmaceutical formulation in a sustained manner.
An oral pharmaceutical formulation comprising:
- oxycodone or a pharmaceutically acceptable salt thereof;
- and
- about 20 mg to 40 mg of naloxone or a pharmaceutically acceptable salt thereof;
- wherein the oxycodone or pharmaceutically acceptable salt thereof and the naloxone or pharmaceutically acceptable salt thereof are present in the pharmaceutical formulation in a weight ratio of 2:1 and are released from the pharmaceutical formulation in a sustained manner.
1 more element
Dependencies are inferred from the claim text.