Antioxidizing intraocular perfusion solution
AssigneeTohoku University
InventorsToru Nakazawa, Takaaki Akaike, Hiroshi Kunikata
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Abstract
The present invention addresses the problem of providing an intraocular irrigating solution that allows the intraocular tissue to be sufficiently protected during ophthalmic surgery and further has high safety. The problem is solved by an intraocular irrigating solution containing at least one of active sulfur molecules of which examples include cysteine persulfide and glutathione persulfide.
Claims5
An intraocular irrigating solution comprising one or more selected from the group consisting of active sulfur molecules represented by Formula (1) and Formula (2), and derivatives of the active sulfur molecules at a concentration of 0.01 μg/mL to 1,000 μg/mL:
- R1—S—(S)n—H (1)
- wherein R1 is selected from the group consisting of L-cysteine (Cys), homocysteine (Hcys), and glutathione (GSH), and n is an integer 1 or more;
- and
- R2—S—(S)n—R3 (2)
- wherein R2 and R3 are independently selected from the group consisting of L-cysteine (Cys), homocysteine (Hcys), and glutathione (GSH), and n is an integer 2 or more.
Dependencies are inferred from the claim text.