Tablet and method of preparing the same
AssigneeBoryung Pharmaceutical Co., Ltd.
InventorsJayhyuk Myung, Sung Chan Jeong, Yun Sam Kim
Life of this patent
Estimating the term…
Abstract
Disclosed is a method for preparing a tablet. The method can improve the compressibility of the active ingredients and produce tablets of uniform quality, bringing about the advantage of increasing tablet hardness with an increase in compression pressure, easily controlling disintegration time, and decreasing tablet friability by using the active ingredient fimasartan, a pharmaceutically acceptable salt thereof or a hydrate or solvate thereof having a specific particle size distribution.
Claims20
A method for preparing a tablet, comprising:
- milling at least 50% (v/v) of an active ingredient based on the total amount of the active ingredient into particles which have a diameter of 10 μm or less, the active ingredient being fimasartan, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof;
- mixing the particles of the milled active ingredient with a pharmaceutically acceptable additive to give a mixture;
- and
- forming the tablet from the mixture.
A tablet, comprising fimasartan, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof as an active ingredient, and a pharmaceutically acceptable additive,
- wherein 50% (v/v) of the active ingredient based on the total amount of the active ingredient is a particle having a diameter of 10 μm or less.
Dependencies are inferred from the claim text.