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US 10,420,727 B2Granted
Pharmaceutical antiretroviral composition
AssigneeCipla Limited
InventorsGeena Malhotra, Shrinivas Purandare
Life of this patent
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Abstract
A pharmaceutical composition comprises at least one integrase inhibitor or its salt, solvate, complex, hydrate, isomer, ester, tautomer, anhydrate, enantiomer, polymorph or prodrug and at least one antiretroviral or anti-HIV agent or its salt, solvate, complex, hydrate, isomer, ester, tautomer, anhydrate, enantiomer, polymorph or prodrug.
Claims11
A pharmaceutical composition that is a single unit dosage form for oral administration in the form of a coated bi-layer tablet comprising a first layer and a second layer,
- wherein the first layer comprises from about 1 mg to about 50 mg dolutegravir or its pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable excipients;
- and
- wherein the second layer comprises from about 150 mg to about 300 mg of tenofovir disoproxil fumarate, from about 150 mg to about 300 mg of lamivudine, and pharmaceutically acceptable excipients.
Dependencies are inferred from the claim text.