Anatomically targeted compression clothing

A method of enhancing sports performance in a mammal, the method comprising applying an item of clothing, configured to be worn against a skin surface of the body of the mammal during a period in which increased performance is desired, said item of clothing comprising a first layer of material having a skin facing surface and an outer surface, the first layer of material is configured to provide general compression or graduated compression to an area of the body, and further comprising a second layer of material formed as an array having at least one pad or protrusion, wherein the array is arranged in a predetermined shape having a width of between 1 and 10 cm such that the array is located and attached on the skin facing surface of the first layer of material adapted to be applied to one or more surface veins in the area of the body, thereby providing targeted compression of at least 20% of a total length of the one or more surface veins, wherein the targeted compression is provided in addition to the general compression or graduated compression, wherein the region of general compression or graduated compression is larger than the at least one array and wherein the at least one array provides a higher level of compression to the one or more surface veins than the first layer of material, the one or more surface veins including a cephalic vein, a basilic vein, a short saphenous vein, a long saphenous vein, a specific plexus of veins, a specific lymphatic plexus, a drainage plexus, and a collection of lymphatic vessels.