Method and system for cardiovascular disease assessment and management

A method for assessing cardiovascular disease in a user with a body region using a mobile computing device comprising a camera module, the method comprising:

• receiving a first time series of image data of the body region of the user, the first time series of image data captured during a daytime period, and the first time series of image data captured at the camera module of the mobile computing device;
• receiving a second time series of image data of the body region of the user, the second time series of image data captured during a nighttime period, and the second time series of image data captured at the camera module of the mobile computing device;
• for each of the first and the second time series of image data:
• generating a photoplethysmogram (PPG) dataset from the respective time series of image data;
• generating a processed PPG dataset, comprising:
• filtering the PPG dataset with a PPG acquisition model generated from historical PPG data, wherein generating the processed PPG dataset is based on the filtered PPG dataset, and wherein the processed PPG dataset is a subset of the PPG dataset;
• fitting a cosinor model to the processed PPG dataset;
• and
• determining a blood pressure parameter value of the user based on the fitted cosinor model, the blood pressure parameter value associated with one of the daytime period and the nighttime period;
• fitting a chronobiological blood pressure model to (1) the blood pressure parameter value associated with the daytime period and (2) the blood pressure parameter value associated with the nighttime period;
• characterizing a diurnal blood pressure variation of the user based on the fitted chronobiological blood pressure model;
• generating an analysis of the diurnal blood pressure variation of the user;
• and
• automatically facilitating therapy provision to the user based upon the analysis.