US 10,414,723 B2Granted

Processes for converting carboxamides to thiocarboxamides

AssigneeVertellus Holdings LLC

InventorsMartin P. Grendze, Ramiah Murugan

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Abstract

Process for converting a carboxamide to a thiocarboxamide includes reacting (a) a substrate that comprises a heteroatom-containing moiety and a carboxamide moiety with (b) a dialkyl dithiophosphate and/or a salt thereof. The heteroatom-containing moiety includes a heteroatom selected from the group consisting of N, O, and S. Processes for preparing piperidine-4-thiocarboxamide are described.

Claims10

Dependent claims

A process for preparing piperidine-4-thiocarboxamide comprising:

reacting piperidine-4-carboxamide with di-(2-methoxyethyl) dithiophosphate and/or a salt thereof in an aromatic solvent.

Dependencies are inferred from the claim text.

Facts

Application: 15/572,451Filed 6 May 2016 · us provisional application
Priority: 8 May 2015
Published: US 2018/0118675 A13 May 2018
Granted: 17 Sep 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07C 327/46
Amides of thiocarboxylic acids: having carbon atoms of thiocarboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
C07B 45/00
Formation or introduction of functional groups containing sulfur
C07C 327/42
Having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms: to hydrogen atoms or to carbon atoms of a…
C07C 327/44
Having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms: to carbon atoms of an unsaturated carbon skeleton

Family

Application62/158,909Us provisional application · filed 8 May 2015
US 2018/0118675 A1Pre-grant publication · published 3 May 2018
US 10,414,723 B2This patent

From the US filing history. Foreign family members aren’t listed.

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