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US 10,398,660 B2Granted
Imaging composition and uses thereof
AssigneeThe University of Melbourne
InventorsPaul Stephen Donnelly, Stacey Erin Rudd, Spencer John Williams
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Abstract
The invention discussed in this application relates to hydroxamic acid-based compounds that are useful as imaging agents when bound to an appropriate metal center, particularly for the imaging of tumors.
Claims6
A conjugate of:
- a compound of formula (I):
- or a pharmaceutically acceptable salt thereof, and
- an antibody,
- wherein L is a leaving group selected from azide, halogen, cyanate and OR, wherein R is selected from C1 to C10 alkyl, C1 to C10 heteroalkyl, C2 to C10 alkene, C2 to C10 alkyne, and aryl, each of which is optionally substituted.
1 more element
Dependencies are inferred from the claim text.