Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof
AssigneeBASF SE
InventorsThomas Subkowski, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel, Ralf Pelzer
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Abstract
The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.
Claims8
A method for the in-vitro or in-vivo modulation of the cold menthol receptor TRPM8, where the receptor is brought into contact with a substance selected from compounds P1 to P31:
- No.
- Formula
- P1
- P2
- P3
- P4
- P5
- P6
- P7
- P8
- P9
- P10
- P11
- P12
- P13
- P14
- P15
- P16
- P17
- P18
- P19
- P20
- P21
- P22
- P23
- P24
- P25
- P26
- P27
- P28
- P29
- P30
- P31
A method for the in-vitro or in-vivo modulation of the cold menthol receptor TRPM8, where the receptor is brought into contact with a composition comprising a substance selected from compounds P1 to P31:
- No.
- Formula
- P1
- P2
- P3
- P4
- P5
- P6
- P7
- P8
- P9
- P10
- P11
- P12
- P13
- P14
- P15
- P16
- P17
- P18
- P19
- P20
- P21
- P22
- P23
- P24
- P25
- P26
- P27
- P28
- P29
- P30
- P31
Dependencies are inferred from the claim text.