Methods of diagnosing and treating Alzheimer's disease with S-equol
AssigneeAusio Pharmaceuticals, LLC
InventorRichard L. Jackson
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Abstract
The present invention provides a method for diagnosing or determining the risk of developing Alzheimer's disease and for treating Alzheimer's disease with S-equol. An aspect of the present invention includes the use of a direct mitochondrial target engagement biomarker to diagnose or assess the risk of developing Alzheimer's disease. Another aspect of the present invention includes the use of a pharmaceutically effective amount of S-equol to treat or prevent Alzheimer's disease in a subject diagnosed with or determined to be at risk of developing Alzheimer's disease.
Claims16
A method for improving a cognitive measurement in a patient at risk of or diagnosed with Alzheimer's disease comprising administering a pharmaceutically effective amount of a formulation comprising S-equol to said patient, wherein there is an absence of genistein, daidzein, and/or IBS003569 in said formulation, and wherein said administration results in an increased ratio of platelet mitochondria cytochrome oxidase (COX) to citrate synthase (CS) in a blood sample obtained from said patient.
Dependencies are inferred from the claim text.