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US 10,386,373 B2Granted
Methods and compositions for assessing antibody specificities
AssigneeSerimmune Inc.
InventorsPatrick Sean Daugherty, Kathryn Vinaya Louise Kamath, Jack Ryan Reifert
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Abstract
The present invention provides compositions and methods that can be used to determine a peptide signature for an antibody repertoire in a sample comprising multiple antibodies. The method can be used to characterize a phenotype in a sample, such as providing a diagnosis, prognosis or theranosis of a medical condition.
Claims28
An array comprising an array surface and at least five peptide probes, wherein each of the at least five peptide probes comprises a binding motif selected from the group consisting of:
- SEQ ID NO:
- 362, SEQ ID NO:
- 364, SEQ ID NO:
- 365, SEQ ID NO:
- 368, SEQ ID NO:
- 369, SEQ ID NO:
- 374, SEQ ID NO:
- 375, SEQ ID NO:
- 376, SEQ ID NO:
- 378, and SEQ ID NO:
- 383, and wherein the at least five peptide probes extend from the array surface.
8 more elements
Dependencies are inferred from the claim text.