Methods and systems for performing navigation-assisted medical procedures

A system for providing feedback on a position of a tool in relation to an item of interest during medical procedures comprising:

• a medical imaging device that obtains image information of an item of interest located within at least a portion of a subject using targeted or non-targeted techniques;
• a tool comprising a sensor, wherein the sensor senses position and orientation information of the tool;
• at least one pair of augmented reality glasses;
• a stereo electro-optical (EO) camera pair with overlapping field-of-views;
• a programmable processor that executes computer-readable instructions, wherein the programmable processor:
• receives the image information of the item of interest from the medical imaging device;
• estimates location information of the item of interest located within at least the portion of the subject using an algorithmic deformation model based on the acquired image information to estimate unobserved motion of the item of interest within at least the portion of the subject;
• receives the position information of the tool;
• determines a relative position of the tool to the item of interest using the location information of the item of interest and the position and orientation information of the tool;
• and
• provides distance and directional feedback based on the relative position of the tool to the item of interest that can be used to change the relative position of the tool to the item of interest during a navigation-assisted medical procedure, wherein the directional feedback includes displaying in the augmented reality glasses a real-time image of the at least a portion of a subject as captured by the EO camera pair with the image information of the item of interest superimposed on the real-time image of the at least a portion of a subject and the distance feedback comprises distance encoded vibration frequencies provided through the tool, wherein the distance and directional feedback changes as the tool moves closer to or further away from the item of interest.