Distinction of infectious virus based on molecular biomarker and neutralization of virus causing food poisoning
AssigneesIndustry Foundation of Chonnam National University, Korea Basic Science Institute
InventorsDu Woon Kim, Joseph Kwon
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Abstract
Discloses are a method for detecting Norovirus using a Norovirus animal model, a method for screening an antivial agent against Norovirus, and a composition for neutralizing the infection with an enteric virus, containing concanavalin A as an active ingredient, so that the method for detecting Norovirus can allow the distinction between infectious Norovirus and non-infectious Norovirus, and the composition can neutralize a virus causing food poisoning.
Claims7
A method for inhibiting gene expression of at least one selected from transferrin receptor-1b (Tfr-1b), heat shock protein 90α (HSP90α), and heat shock cognate 71 (HSC71) in a subject, comprising:
- administering to the subject an effective amount of a composition comprising concanavalin A (Con A),
- wherein Tfr-1b, HSP90α, and HSC71 expression levels are increased due to Norovirus infection.
A method for neutralizing infectivity of Norovirus virions comprising administering to a subject in need thereof an effective amount of a composition comprising concanavalin A (Con A).
Dependencies are inferred from the claim text.