Transcriptome estimation device and transcriptome estimation method
AssigneeThe University of Tokyo
InventorsYuichi Wakamoto, Koseki Kobayashi
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AssigneeThe University of Tokyo
InventorsYuichi Wakamoto, Koseki Kobayashi
Estimating the term…
An objective cell is irradiated with laser beam of a predetermined wavelength. Only Stokes light is selected out of detected light including reflected light and scattered light of the laser beam, and a Raman scattering spectrum is obtained by dispersion of the selected Stokes light. A transcriptome of the objective cells is estimated, based on the Raman scattering spectrum. It is preferable to estimate the transcriptome of the objective cells, based on N-dimensional Raman data obtained by dimensional reduction of the Raman scattering spectrum. This configuration only needs to irradiate the objective cell with the laser beam and does not require to destroy the objective cell. As a result, this enables the transcriptome of the cell to be estimated in a short time period without destroying the cell.
A transcriptome estimation device configured to estimate a transcriptome of an objective cell, the transcriptome estimation device comprising:
A transcriptome estimation method that estimates a transcriptome of an objective cell from a Raman scattering spectrum that is obtained by irradiation of the objective cell with laser beam of a predetermined wavelength,
Dependencies are inferred from the claim text.