US 10,378,001 B2 · Subtilase variants and compositions comprising same

Abstract

The present invention relates to novel subtilase variants exhibiting increased stability and optionally on par or improved wash performance. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.

Claims11

Dependent claims

A subtilase variant having protease activity, wherein said variant comprises substitutions at positions corresponding to positions 61, 194 and 261 of amino acids 1 to 275 of SEQ ID NO:

2, wherein the variant comprises E, P and D, respectively, at positions corresponding to positions 61, 194 and 261 of SEQ ID NO:
2, and wherein said variant is
a polypeptide that has at least 90% but less than 100% sequence identity to amino acids 1-269 of the polypeptide of SEQ ID NO:
4.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

14/899,583Filed 27 Jun 2014

Priority

EP 1317406527 Jun 2013

Published

US 2016/0137998 A119 May 2016

Granted

13 Aug 2019

Term ends

Not estimatedThe source records don’t support an estimate.

Classification9 codes

C12N 9/54
Derived from bacteria or Archaea: bacteria being Bacillus
C11D 3/386
Products with no well-defined composition , e.g. natural products: preparations containing enzymes , e.g. protease or amylase
C11D 3/38681
Preparations containing enzymes , e.g. protease or amylase: chemically modified or immobilised enzymes
C12N 9/6424
From mammals: serine endopeptidases

Subtilase variants and compositions comprising same

Life of this patent

Subtilase variants and compositions comprising same

Life of this patent

Abstract

Claims11