Anti-BAFF antibodies
AssigneeBoehringer Ingelheim International GmbH
InventorsScott Ronald Brodeur, Keith A. Canada, Michael Dziegelewski, Philip Nicholas Gorman, Pankaj Gupta, Ashraf Khalil, John J. Miglietta, Amy Marie Nicoletti, Qi Pan, David Presky, Sanjaya Singh, Tao Wu, Haiguang Xiao
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Abstract
The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
Claims10
An isolated polynucleotide comprising a sequence encoding a light chain variable region of any one of the amino acid sequences of SEQ ID NOS:
- 82-97, or a heavy chain variable region of any one of the amino acid sequences of SEQ ID NOS:
- 100-115.
An isolated polynucleotide comprising a sequence encoding a light chain variable region amino acid sequence of SEQ ID NO:
- 82, or a heavy chain variable region amino acid sequence of SEQ ID NO:
- 101.
An isolated polynucleotide comprising a sequence encoding a light chain variable region amino acid sequence of SEQ ID NO:
- 88, or a heavy chain variable region amino acid sequence of SEQ ID NO:
- 101.
An isolated polynucleotide comprising a sequence encoding a light chain variable region amino acid sequence of SEQ ID NO:
- 94, or a heavy chain variable region amino acid sequence of SEQ ID NO:
- 112.
An isolated polynucleotide comprising a sequence encoding a light chain variable region amino acid sequence of SEQ ID NO:
- 93, or a heavy chain variable region amino acid sequence of SEQ ID NO:
- 114.
Dependencies are inferred from the claim text.