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US 10,377,744 B2Granted
Potent soluble epdxide hydrolase inhibitors
AssigneeEicosis, LLC
InventorsBruce D. Hammock, Kin Sing Stephen Lee, Ahmet Bora Inceoglu
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Abstract
The invention discloses a new series of inhibitors of soluble epoxide hydrolase (sEH) with improved physical properties that enhance their druglikeness to treat sEH associated diseases such as chronic diabetic neuropathic pain.
Claims2
A compound, wherein the compound is (S)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)-3-(1-(2-methylbutanoyl)piperidin-4-yl)urea (Compound 26)
- or pharmaceutically acceptable salt thereof.
A compound having the structure:
Dependencies are inferred from the claim text.