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US 10,377,731 B2Granted
Compositions and methods for cancer treatment
AssigneeBoston Biomedical, Inc.
InventorsChiang Jia Li, Keith Mikule, Youzhi Li
Life of this patent
Estimating the term…
Abstract
The present invention relates to the composition and methods of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer.
Claims3
A method for treating cancer in a human subject in need thereof comprising administering to said subject
- a therapeutically effective amount of synthetic 2-acetylnaphtho[2,3-b]furan-4,9-dione, and
- a therapeutically effective amount of at least one agent chosen from bevacizumab, bortezomib, capecitabine, cetuximab, fluorouracil, imatinib, irinotecan, leucovorin, oxaliplatin, panitumumab, pemetrexed, temozolomide, cisplatin, paclitaxel, erlotinib, sunitinib, lapatinib, sorafenib, carboplatin, doxorubicin, docetaxel, gemcitabine, and etoposide,
- wherein said cancer is pancreatic cancer or colorectal cancer,
- wherein said cancer expresses activated STAT3.
1 more element
Dependencies are inferred from the claim text.