Anticancer agent

A compound represented by the formula (IA):

• wherein
• each R1 is independently
• hydrogen,
• halogen,
• hydroxy,
• amino,
• cyano,
• nitro,
• C1-12 alkyl,
• C2-6 alkenyl,
• C2-6 alkynyl,
• C3-7 cycloalkyl,
• C3-7 cycloalkenyl,
• aryl,
• a heterocyclyl group,
• C1-6 alkoxy,
• aryloxy,
• C1-6 alkylthio, or
• arylthio, or
• two R1 bonded to the adjacent carbon atoms on a benzene ring are optionally joined to form C1-4 alkylenedioxy,
• R2is
• C1-12 alkyl optionally substituted by substituent(s) selected from substituent group α,
• C2-6 alkenyl optionally substituted by substituent(s) selected from substituent group α,
• C2-6 alkynyl optionally substituted by substituent(s) selected from substituent group α,
• C3-7 cycloalkyl optionally substituted by substituent(s) selected from substituent group α,
• aryl optionally substituted by substituent(s) selected from substituent group α,
• aryl C1-6 alkyl optionally substituted by substituent(s) selected from substituent group α, or
• heterocyclyl optionally substituted by substituent(s) selected from substituent group α,
• R3 is
• hydrogen,
• halogen,
• cyano,
• nitro,
• C1-12 alkyl,
• C2-6 alkenyl,
• C2-6 alkynyl,
• C3-7 cycloalkyl,
• C3-7 cycloalkenyl,
• aryl,
• heterocyclyl,
• C1-6 alkoxy,
• aryloxy,
• C1-6 alkylthio, or
• arylthio,
• n is an integer of 1-4 when R1 is hydrogen,
• n is an integer of 1 or 2 when R1 is not hydrogen, and
• the substituent group α consists of
• halogen,
• hydroxy,
• optionally substituted amino,
• carboxy,
• C1-6 alkoxycarbonyl,
• sulfo group,
• phosphoric acid group,
• di C1-6 alkyl phosphoric acid group,
• cyano,
• optionally substituted C1-6 alkyl,
• C3-7 cycloalkyl,
• C3-7 cycloalkyl C1-6 alkyl,
• optionally substituted C1-6 alkoxy,
• C1-6 alkylthio,
• optionally substituted aryl,
• optionally substituted aryloxy,
• aryl C1-6 alkoxy,
• optionally substituted heterocyclyl,
• optionally substituted C1-6 alkylcarbonyl,
• heterocyclylcarbonyl,
• optionally substituted C1-6 alkylcarbonyloxy,
• optionally substituted C3-7 cycloalkylcarbonyloxy,
• arylcarbonyloxy,
• monocyclic heterocyclylcarbonyloxy,
• optionally substituted C1-6 alkoxycarbonyloxy,
• optionally substituted heterocyclyl C1-6 alkoxycarbonyloxy,
• C3-7 cycloalkyloxycarbonyloxy,
• heterocyclyloxycarbonyloxy,
• optionally substituted heterocyclyloxy,
• tri C1-6 alkylammonio,
• optionally substituted C1-6 alkylsulfonyl and
• C1-6 alkylsulfamoylcarbonyl,
• or a pharmaceutically acceptable salt thereof.