Back to results
US 10,376,885 B2Granted
Microfluidic concentrator for label-free, continuous nanoparticle processing
AssigneeLehigh University
InventorsXuanhong Cheng, Chao Zhao, Alparslan Oztekin
Life of this patent
Estimating the term…
Abstract
Disclosed herein are apparatuses comprising, for example, a microfluidic channel device comprising a main body comprising a channel configured to provide for helical fluid motion of material within the channel; and a temperature control system that applies a temperature gradient to the channel. Methods of making and using the apparatus are also described.
Claims16
An apparatus comprising:
- a microfluidic channel device comprising a main body comprising a channel configured to provide for helical fluid motion of material within the channel;
- and
- a temperature control system that applies a temperature gradient to the channel;
- wherein the channel comprises microgrooves that initiate and maintain the helical fluid motion of the material within the channel, and the channel is between 500 to 2000 μm in width, between 50 to 100 μm in height, and between 1 to 40 cm in length;
- wherein the apparatus is configured such that the material undergoes thermophoresis and swirling transport, which are induced by said microgrooves over a surface of the microfluidic channel.
2 more elements
A method of using an apparatus, the method comprising:
- providing a microfluidic channel device comprising a main body comprising a channel configured to provide for helical fluid motion of material within the channel;
- providing a continuous flow of the material within the channel;
- and
- applying a temperature gradient to the channel using a temperature control system;
- causing the material to undergo thermophoresis and swirling transport as it flows through the channel;
- and wherein the channel comprises microgrooves that initiate and maintain the helical fluid motion of the material within the channel, and the channel is between 500 to 2000 μm in width, between 50 to 100 μm in height, and between 1 to 40 cm in length.
3 more elements
Dependencies are inferred from the claim text.