Process for extraction and separation of oxyresveratrol from Artocarpus lakoocha Roxb
AssigneeCouncil of Scientific and Industrial Research
InventorsSwapnali Hazarika, Dilip Konwar, Hirokjyoti Borah, Somiron Borthakur, Pranab Barkakati, Mohan Modon Bora, Ram Nath Das
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Abstract
The present invention relates to a process for separation of oxyresveratrol molecule from the extracted solution of Artocarpus lakoocha Roxb. through membrane application. The product can be obtained in excellent yield upto 81% in case of extraction using water as solvent and can be separated from the extracted mixture upto 98% using indigenously developed nanofiltration membrane. Only the desired Trans isomer is obtained and no cis isomerization takes place during the extraction process.
Claims8
A process for extraction and separation of oxyresveratrol from heartwood of Artocarpus lakoocha Roxb., said process comprising the steps of:
- (i) mixing Artocarpus lakoocha Roxb. Powder obtained from the heartwood with water at a temperature in the range of 30° C.-70° C. for 1 to 10 hours to extract a solution and filtering the solution to obtain a solution enriched in oxyresveratrol;
- (ii) subjecting the solution enriched in oxyresveratrol obtained in step (i) to a membrane treatment in a two compartment membrane cell containing a nanofiltration membrane selected from an Alpha cyclodextrin-polysulfone composite nanofiltration membrane, a Beta cyclodextrin-polysulfone composite nanofiltration membrane or a Gamma cyclodextrin-polysulfone composite nanofiltration membrane by circulating through the nanofiltration membrane with a peristaltic pump at a flow rate in the range of 42.50 ml/min to 107.14 ml/min to obtain oxyresveratrol;
- and
- (iii) collecting the oxyresveratrol obtained in step (ii) from feed side of the membrane;
- wherein the trans membrane pressure across the membrane in step (ii) is maintained within the range of 7.2 psi to 21.75 psi.
Dependencies are inferred from the claim text.