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US 10,376,615 B2Granted
Micro-needle and micro-needle patch
AssigneeSmall Lab Co., Ltd.
InventorsJeong Gyu Lee, Chang Hyeon Kim
Life of this patent
Estimating the term…
Abstract
Provided are micro-needles and a micro-needle patch for transdermal delivery of a pharmaceutical, medical, or cosmetic substance. The micro-needle may include a biocompatible matrix having a micro-needle-like shape; and porous particles provided at at least a portion of a surface or the interior of the biocompatible matrix.
Claims18
A micro-needle comprising:
- a biocompatible matrix having a micro-needle-like shape and having a first material configured to be swollen or dissolved in a living tissue;
- and
- particles provided at at least a portion of a surface or an interior of the biocompatible matrix,
- wherein the particles have a particle body and a plurality of pores formed therein,
- wherein the particle body comprises a second material different from the first material,
- wherein the particles function as drug carriers containing pharmaceutically, medically, or cosmetically effective substance for delivering the pharmaceutically, medically, or cosmetically effective substance to the living tissue,
- wherein the effective substance is trapped in the plurality of pores of the particles,
- wherein the plurality of pores of the particles comprise open or closed pores, and at least one of porosity, size and opening of the open or closed pores is controlled to control a speed of releasing the effective substance in the living tissue,
- wherein the porosity of the particles has a range from 5% to 90%.
6 more elements
A micro-needle comprising:
- a biocompatible matrix having a micro-needle-like shape and having a first material configured to be swollen or dissolved in a living tissue;
- and
- particles provided at at least a portion of a surface or an interior of the biocompatible matrix,
- wherein the particles have a particle body and a plurality of pores formed therein,
- wherein the particle body comprises a second material different from the first material,
- wherein the particles function as drug carriers containing pharmaceutically, medically, or cosmetically effective substance for delivering the pharmaceutically, medically, or cosmetically effective substance,
- wherein the effective substance is dispersed in matrixes of the particles, and the pores of the particles comprise open or closed pores with opening controlled to control a speed of releasing the effective substance in the living tissue,
- wherein the porosity of the particles has a range from 5% to 90%.
5 more elements
A micro-needle comprising:
- a biocompatible matrix containing a bio-derived soluble substance and having a first material configured to be swollen or dissolved in a living tissue;
- and
- particles provided at a portion of a surface of the biocompatible matrix,
- wherein average size of the particles is from about 0.01 μm to about 100 μm,
- wherein the particles have a particle body and a plurality of pores formed therein,
- wherein the particle body comprises a second material different from the first material,
- wherein the particles function as drug carriers containing pharmaceutically, medically, or cosmetically effective substance for delivering the pharmaceutically, medically, or cosmetically effective substance,
- wherein the effective substance is trapped in the plurality of pores of the particles,
- wherein the plurality of pores of the particles comprise open or closed pores, and at least one of porosity, size and opening of the open or closed pores is controlled to control a speed of releasing the effective substance,
- wherein the porosity of the particles has a range from 5% to 90%.
7 more elements
Dependencies are inferred from the claim text.