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US 10,376,590 B2Granted
Sustained delivery formulations of risperidone compound
AssigneeIndivior UK Limited
InventorsEric Dadey, Qi Li, Christopher Lindemann
Life of this patent
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AssigneeIndivior UK Limited
InventorsEric Dadey, Qi Li, Christopher Lindemann
Estimating the term…
The present invention relates to a risperidone sustained release delivery system for treatment of medical conditions relating to delusional psychosis, schizophrenia, bipolar disorder, psychotic depression, obsessive-compulsion disorder, Tourette syndrome, and autistic spectrum disorders. The sustained release delivery system includes a flowable composition containing risperidone, a metabolite, or a prodrug thereof and an implant containing risperidone, a metabolite, or a prodrug thereof. The flowable composition may be injected into tissue whereupon it coagulates to become a solid or gel, monolithic implant. The flowable composition includes a biodegradable, thermoplastic polymer, an organic liquid, and risperidone, a metabolite or a prodrug thereof.
A method of treating schizophrenia in a subject in need thereof, the method comprising subcutaneously injecting the subject with a composition comprising risperidone base in a solution comprising:
A method of treating schizophrenia in a subject in need thereof, the method comprising subcutaneously injecting the subject with a composition comprising about 10 wt % to about 30 wt % risperidone base in a solution comprising:
Dependencies are inferred from the claim text.