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US 10,376,562 B2Granted
Methods for promoting wound healing and hair growth comprising GDNF administration
AssigneeThe Jackson Laboratory
InventorsRobert E. Braun, Manju Sharma
Life of this patent
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Abstract
The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.
Claims13
A method for promoting hair growth on a subject, the method comprising the steps of:
- (a) administering at a site of desired hair growth on said subject a composition comprising a pharmaceutically effective dose of an isolated glial cell derived neurotrophic factor (GDNF), wherein said GDNF consists of residues 78-211 of SEQ ID NO:7 or residues 118-211 of SEQ ID NO:7;
- and (b) repeating said administrating step for a time period sufficient to promote said hair growth on said subject.
Dependencies are inferred from the claim text.