Alkylated imino sugars exhibiting glucosidase inhibition and their method of use

A method of treating a flavivirus infection said method comprising administering to a subject an effective amount of at least one compound having formula (III):

• including hydrates, solvates, pharmaceutically acceptable salts, and complexes thereof, wherein:
• R1 at each occurrence is independently selected from the group consisting of hydrogen and COR4;
• R5 is selected from a group consisting of optionally substituted C1-6 alkyl, optionally substituted branched C1-6 alkyl, optionally substituted cyclic C3-8 alkyl, optionally substituted C5-C10 bicylcoalkyl, optionally substituted aryl which may be substituted by 0-5 moieties, OR5, and NHR6;
• R3 is selected from a group consisting of optionally substituted C1-6 alkyl, optionally substituted branched C1-6 alkyl, optionally substituted cyclic C3-8 alkyl, 1-adamantyl, 2-adamantyl, optionally substituted C5-C10 bicylcoalkyl, and optionally substituted aryl which may be substituted by 0-5 moieties;
• R3 and R5 are taken together with the atom to which they are bound to form an optionally substituted ring having 5 ring atoms;
• R3 and R5 are taken together with the atom to which they are bound to form an optibonally substituted ring having 5 ring atoms;
• R3and R5 are taken together with the atom to which they are bound to form
• R3 and R5 are taken together with the atom to which they are bound to form
• R4 at each occurrence is independently selected from the group consisting of optionally substituted C1-6 alkyl and optionally substituted branched C1-6 alkyl;
• R5 is selected from a group consisting of an optionally substituted C1-6 alkyl, optionally substituted branched C1-6 alkyl, optionally substituted cyclic C3-8 alkyl, optionally substituted C5 -C10bicyicoalkyl, optionally substituted aryl which may be substituted by 0-5 moieties;
• R6is selected from a group consisting of hydrogen, an optionally substituted C1-6 alkyl, optionally substituted branched C1-6 alkyl, optionally substituted cyclic C3-8alkyl, optionally substituted C5-10 bicylcoalkyl, optionally substituted aryl which may be substituted by 0-5 moieties;
• and
• R7a, R7b,R7c and R7d are each selected from a group consisting of hydrogen, halogen, optionally substituted C1-6 alkyl, optionally substituted branched C1-6 alkyl, and optionally substituted C1-6 alkoxy.