Bolus dose of hydroxycitric acid with glycerol
AssigneeGlykon Technologies Group, LLC
InventorsDallas L. Clouatre, Daniel E. Clouatre, Brad J. Douglass
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Abstract
A method of delivering a daily dose of hydroxycitric acid in the form of a salt as a single bolus that is as effective or more so than the same amount of active delivered via two or three administrations (b.i.d. or t.i.d.) using current delivery modalities. The method reduces the rate of occurrence of common adverse events with hydroxycitric acid salts, and reduces the occurrence of reverse effects on diets high in fat and/or alcohol. The method improves the uptake of the active compound thereby reducing the dose required.
Claims12
A sealed dosage container, consisting essentially of:
- an aqueous solution of a hydroxycitrate salt in combination with glycerol, wherein the hydoxycitrate salt is present in the sealed container in amount of 3.0 g to 4.5 g±20%, and the glycerol is present in the container in an amount in a range of from 1.0 g to 4.0 g±20%, and a therapeutically active agent selected from the group consisting of a green coffee bean extract, a bitter melon extract, and sesame lignan extract, and
- wherein the liquid sealed dosage is prepared by a process consisting essentially of the steps of:
- mixing glycerol, and purified water wherein the glycerol is present in an amount of about 1 to 3 parts by volume and the purified water is present in an amount of about 3 to 1 parts by volume to create a glycerol and purified water solution;
- and
- dissolving the hydroxycitrate salt in the glycerol and purified water solution to obtain an hydroxycitrate salt concentration ranging from about 1.1 to 1.7 molar dosage;
- and
- adding the active agent.
Dependencies are inferred from the claim text.