System and method for performing renal denervation verification
AssigneePacesetter, Inc.
InventorsEric S. Fain, Martin Cholette, Gary R. Dulak, Gene A. Bornzin, John W. Poore
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Abstract
A renal denervation feedback method is described that performs a baseline measurement of renal nerve plexus electrical activity at a renal vessel; denervates at least some tissue proximate the renal vessel after performing the baseline measurement; performs a post-denervation measurement of renal nerve plexus electrical activity at the renal vessel, after the denervating; and assesses denervation of the renal vessel based on a comparison of the baseline measurement and the post-denervation measurement of renal nerve plexus electrical activity at the renal vessel.
Claims16
A renal denervation feedback method comprising:
- performing a baseline measurement of intrinsic renal nerve plexus electrical activity at a renal vessel by monitoring compound action potentials including baseline afferent and efferent signals;
- denervating at least some tissue at a denervation location proximate the renal vessel after performing the baseline measurement;
- performing a post-denervation measurement of intrinsic renal nerve plexus electrical activity at a measurement location on a distal side of the denervation location by monitoring post-denervation compound action potentials, after the denervating;
- and
- determining the denervation is complete when the post-denervation compound action potentials include solely afferent signals.
A renal denervation feedback system comprising:
- at least one denervation member to denervate at least some tissue at a denervation location proximate a renal vessel;
- at least one measurement member to perform a baseline measurement of intrinsic renal nerve plexus electrical activity, including baseline afferent and efferent signals, at the renal vessel before denervation of the at least some tissue proximate the renal vessel and to perform a post-denervation measurement of renal nerve plexus electrical activity at a measurement location on a distal side of the denervation location after the denervation, the baseline and post-denervation measurements acquired by monitoring compound action potentials;
- and
- a denervation assessment module to assess denervation of the renal vessel based on a comparison of the baseline measurement and the post-denervation measurement of renal nerve plexus electrical activity at the renal vessel, wherein the denervation assessment module is configured to determine the denervation is complete when the post-denervation compound action potentials include solely afferent signals.
Dependencies are inferred from the claim text.