# US 10,373,349 B2 · Image generation apparatus > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,373,349 B2 - Document ID: US10373349B2 - Status: Granted - Kind: B2 - Application number: 15/125,608 - Filed: 2015-03-18 - Published: 2017-01-05 - Granted: 2019-08-06 - Earliest claimed: 2014-03-26 - Assignees: Koninklijke Philips N.V. - Applicants: Koninklijke Philips N.V. - Inventors: Thomas Koehler; Axel Thran; Frank Bergner; Bernhard Johannes Brendel; Rolf Dieter Bippus - Web page: https://patentgrep.com/patent/US10373349B2 ## CPC - G06T 12/20: Inverse problem, i.e. transformations from projection space into object space - G06T 2211/408: Dual energy - G06T 2211/424: Iterative - G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL ## Abstract The invention relates to an image generation apparatus (1) for generating an image of an object. A reconstruction unit (10) reconstructs the image based on provided measured projection values such that costs defined by a cost function are reduced, wherein the cost function depends on differences between calculated projection values, which have been determined by simulating a forward projection through the image, and the provided measured projection values, and wherein a degree of dependence of the cost function on a respective difference depends on the respective difference. This can allow for a consideration of a degree of disturbance of the measured projection values by motion and/or by an incomplete illumination of the object during the reconstruction process, which can lead to a reconstruction of an image having an improved image quality. ## Claims ### Claim 1 An image generation apparatus for generating an image of an object, the image generation apparatus comprising: a detection device for providing measured projection values of the object, a computer for reconstructing the image based on the provided measured projection values such that costs defined by a cost function are reduced, wherein the cost function depends on differences between calculated projection values, which have been determined by simulating a forward projection through the image, and the provided measured projection values, and wherein the cost function depends a first difference of the differences weighted by a first weight and a second difference of the differences weighted by a second weight, and the second weight is smaller than the first weight. ### Claim 2 (depends on 1) The image generation apparatus as defined in claim 1, wherein the cost function is adapted to depend stronger on a respective difference relative to the other differences, if the respective difference is smaller than a threshold, and to depend less on a respective difference relative to the other differences, if the respective difference is larger than the threshold. ### Claim 3 (depends on 2) The image generation apparatus as defined in claim 2, wherein the threshold depends on the standard deviation of the measured projection value to which the respective difference corresponds. ### Claim 4 (depends on 1) The image generation apparatus as defined in claim 1, wherein the cost function is adapted to depend quadratically on a respective difference, if the respective difference is smaller than a threshold, and to depend linearly on a respective difference, if the respective difference is larger than the threshold. ### Claim 5 (depends on 1) The image generation apparatus as defined in claim 1, wherein the cost function is adapted such that the degree of dependence of the cost function on the respective difference further depends on the standard deviation of the measured projection value to which the respective difference corresponds. ### Claim 6 (depends on 1) The image generation apparatus as defined in claim 1, wherein the cost function is adapted to further depend on the standard deviation of the measured projection value to which the respective difference corresponds, wherein the cost function is adapted to depend stronger on the standard deviation of the measured projection value to which the respective difference corresponds, if the respective difference is smaller than a threshold, and to depend less on the standard deviation of the measured projection value to which the respective difference corresponds, if the respective difference is larger than the threshold. ### Claim 7 (depends on 1) The image generation apparatus as defined in claim 1, wherein each of the measured projection values is generated based on a measurement of radiation, which has been generated by a radiation source, after having traversed an object along a radiation path. ### Claim 8 (depends on 7) The image generation apparatus as defined in claim 7, wherein for at least one of the radiation paths, plural projection values are generated, each projection value being generated in accordance with one of plural materials. ### Claim 9 (depends on 8) The image generation apparatus as defined in claim 8, wherein the cost function depends on a transform of a vector specifying the differences between the measured projection values and the calculated projection values for one radiation path and the plural materials or on a set of transforms of vectors specifying the difference between the measured and the calculated projection values for plural radiation paths and the plural materials, each transform being calculated based on eigenvectors of a covariance matrix indicating covariances between the measurements of projection values for the plural materials. ### Claim 10 (depends on 1) The image generation apparatus as defined in claim 1, wherein each set of differences includes differences calculated for projection values measured at adjacent locations and/or consecutive detection times. ### Claim 11 An image generation method for generating an image of an object, the image generation method comprising: providing measured projection values of the object by a measured projection values providing unit, reconstructing the image based on the provided measured projection values such that costs defined by a cost function are reduced by a reconstruction unit, wherein the cost function depends on differences between calculated projection values, which have been determined by simulating a forward projection through the image, and the provided measured projection values, and wherein the cost function depends a first difference of the differences weighted by a first weight and a second difference of the differences weighted by a second weight, and the second weight is smaller than the first weight. ### Claim 12 A non-transitory computer readable medium storing instructions that when executed by a computer cause the computer to perform a method comprising: providing measured projection values of the object by a measured projection values providing unit, reconstructing the image based on the provided measured projection values such that costs defined by a cost function are reduced by a reconstruction unit, wherein the cost function depends on differences between calculated projection values, which have been determined by simulating a forward projection through the image, and the provided measured projection values, and wherein the cost function depends a first difference of the differences weighted by a first weight and a second difference of the differences weighted by a second weight, and the second weight is smaller than the first weight. ### Claim 13 (depends on 11) The method as defined in claim 11, wherein the cost function is adapted to depend stronger on a respective difference relative to the other differences, if the respective difference is smaller than a threshold, and to depend less on a respective difference relative to the other differences, if the respective difference is larger than the threshold. ### Claim 14 (depends on 13) The method as defined in claim 13, wherein the threshold depends on the standard deviation of the measured projection value to which the respective difference corresponds. ### Claim 15 (depends on 11) The method as defined in claim 11, wherein the cost function is adapted to depend quadratically on a respective difference, if the respective difference is smaller than a threshold, and to depend linearly on a respective difference, if the respective difference is larger than the threshold. ### Claim 16 (depends on 11) The method as defined in claim 11, wherein the cost function is adapted such that the degree of dependence of the cost function on the respective difference further depends on the standard deviation of the measured projection value to which the respective difference corresponds. ### Claim 17 (depends on 11) The method as defined in claim 11, wherein the cost function is adapted to further depend on the standard deviation of the measured projection value to which the respective difference corresponds, wherein the cost function is adapted to depend to a greater degree on the standard deviation of the measured projection value to which the respective difference corresponds, if the respective difference is smaller than a threshold, and to depend to a lesser degree on the standard deviation of the measured projection value to which the respective difference corresponds, if the respective difference is larger than the threshold. ### Claim 18 (depends on 11) The method as defined in claim 11, wherein each of the measured projection values is generated based on a measurement of radiation, which has been generated by a radiation source, after having traversed an object along a radiation path. ### Claim 19 (depends on 18) The method as defined in claim 18, wherein for at least one of the radiation paths, plural projection values are generated, each projection value being generated in accordance with one of plural materials. ### Claim 20 (depends on 19) The method as defined in claim 19, wherein the cost function depends on a transform of a vector specifying the differences between the measured projection values and the calculated projection values for one radiation path and the plural materials or on a set of transforms of vectors specifying the difference between the measured and the calculated projection values for plural radiation paths and the plural materials, each transform being calculated based on eigenvectors of a covariance matrix indicating covariances between the measurements of projection values for the plural materials.