# US 10,373,309 B2 · Method to support tumor response measurements

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- Number: US 10,373,309 B2
- Document ID: US10373309B2
- Status: Granted
- Kind: B2
- Application number: 15/028,738
- Filed: 2014-10-13
- Published: 2016-09-22
- Granted: 2019-08-06
- Earliest claimed: 2013-10-23
- Assignees: Koninklijke Philips N.V.
- Applicants: Koninklijke Philips N.V.
- Inventors: Frank Olaf Thiele; Martin Weibrecht
- Web page: https://patentgrep.com/patent/US10373309B2

## CPC

- G06T 11/60: Creating or editing images; Combining images with text
- G06F 3/04812: Interaction techniques based on cursor appearance or behaviour, e.g. being affected by the presence of displayed objects
- G06F 3/04845: for image manipulation, e.g. dragging, rotation, expansion or change of colour
- G06F 3/0485: Scrolling or panning
- G06T 7/0012: {Biomedical image inspection}
- G06T 7/50: Depth or shape recovery
- A61B 5/1075: {for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer (A61B8/0858 takes precedence)}
- A61B 6/12: Arrangements for detecting or locating foreign bodies
- A61B 2576/00: Medical imaging apparatus involving image processing or analysis (A61B1/00009, A61B6/52 and A61B8/52 take precedence)
- G06T 2207/10081: Computed x-ray tomography [CT]
- G06T 2207/10088: Magnetic resonance imaging [MRI]
- G06T 2207/10104: Positron emission tomography [PET]
- G06T 2207/30096: Tumor; Lesion
- G16H 30/40: for processing medical images, e.g. editing
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

A method comprises the step of determining a minimum length of a lesion based on an imaging modality used to capture an image of the lesion and a slice thickness of the image, generating an extent cursor corresponding to the minimum size of the lesion, the extent cursor having a circular shape with a diameter corresponding to the minimum length and displaying the image of the lesion with the extent cursor positioned thereover.

## Claims

### Claim 1

A method, comprising:
determining a minimum length of a measurable lesion according to a selected standard based on an imaging modality used to capture an image of a lesion and a slice thickness of the image;
generating an extent cursor conforming with the minimum length of the measurable lesion according to the selected standard, the extent cursor having a circular shape with a diameter corresponding to the minimum length; and
displaying the image of a lesion with the extent cursor positioned thereover.

### Claim 2 (depends on 1)

The method of claim 1, wherein the extent cursor is automatically displayed on the image.

### Claim 3 (depends on 1)

The method of claim 1, wherein a position of the extent cursor on the image is adjustable via a user interface.

### Claim 4 (depends on 1)

The method of claim 1, further comprising the step of operating a user interface to remove the extent cursor from a display.

### Claim 5 (depends on 4)

The method of claim 4, further comprising the step of operating a user interface to display an extent scale over the image, the extent scale having a length corresponding to the minimum length.

### Claim 6 (depends on 5)

The method of claim 5, wherein the extent scale may be positioned and rotated via the user interface.

### Claim 7 (depends on 1)

The method of claim 1, further comprising the step of closing the image and displaying an additional image of the lesion.

### Claim 8 (depends on 7)

The method of claim 7, wherein when the additional image is displayed, the extent cursor is removed and a warning is generated.

### Claim 9 (depends on 7)

The method of claim 7, wherein the additional image including one or both of an additional extent cursor and an additional extent scale selected to conform to imaging specification of the additional image.

### Claim 10 (depends on 1)

The method of claim 1, wherein a plurality of images is displayed side by side on a single display with their respective extent cursors and/or extent scales.

### Claim 11 (depends on 1)

The method of claim 1, wherein the image is three-dimensional and the extent cursor is spherical.

### Claim 12 (depends on 1)

The method of claim 1, wherein a predetermined algorithm is used to determine the minimum length of the measurable lesion.

### Claim 13 (depends on 1)

The method of claim 1, wherein the imaging modality is one of: computer tomography (CT), a magnetic resonance imaging (MRI), an X-ray, and a lymph node assessment.

### Claim 14 (depends on 1)

The method of claim 1, wherein the selected standard is one of: response evaluation criteria in solid tumors (RECIST), positron emission response criterial in solid tumors (PERCIST); and Revised Assessment in Neuro-Oncology (RANO).

### Claim 15 (depends on 1)

The method of claim 1, wherein the extent cursor has a nonadjustable size.

### Claim 16

A system for assessing lesions, comprising:
a processor for determining a minimum length of a measurable lesion according to a selected standard based on an imaging modality used to capture an image of the lesion and a slice thickness of the image, the processor being further configured for generating an extent cursor conforming with the minimum length of the measurable lesion according to the selected standard, the extent cursor having a circular shape with a diameter corresponding to the minimum length and displaying the image of a lesion with the extent cursor positioned thereover.

### Claim 17 (depends on 16)

The system of claim 16, wherein the processor permits scrolling through an additional image of the measurable lesion with the extent cursor remaining in position over the measurable lesion while a user toggles between a plurality of images.

### Claim 18 (depends on 16)

The system of claim 16, wherein the imaging modality is one of: computer tomography (CT), a magnetic resonance imaging (MRI), an X-ray, and a lymph node assessment.

### Claim 19 (depends on 16)

The system of claim 16, wherein the selected standard is one of: response evaluation criteria in solid tumors (RECIST), positron emission response criterial in solid tumors (PERCIST); and Revised Assessment in Neuro-Oncology (RANO).

### Claim 20 (depends on 16)

The system of claim 16, wherein the processor is further configured to generate an extent scale over the image, the extent scale having a length corresponding to the minimum length.

### Claim 21 (depends on 16)

The system of claim 16, wherein the extent cursor has a nonadjustable size.

### Claim 22 (depends on 1)

A non-transitory computer-readable storage medium including a set of instructions executable by a processor, the set of instructions operable to carry out the method of claim 1.
