# US 10,370,411 B2 · Beta-hairpin peptidomimetics

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 10,370,411 B2
- Document ID: US10370411B2
- Status: Granted
- Kind: B2
- Application number: 15/791,087
- Filed: 2017-10-23
- Published: 2018-02-15
- Granted: 2019-08-06
- Earliest claimed: 2013-03-30
- Assignees: Polyphor AG
- Applicants: Polyphor AG
- Inventors: Daniel Obrecht; Anatol Luther; Francesca Bernardini; Peter Zbinden
- Web page: https://patentgrep.com/patent/US10370411B2

## CPC

- C07K 7/64: Cyclic peptides containing only normal peptide links
- A61P 1/00: Drugs for disorders of the alimentary tract or the digestive system
- A61P 1/04: for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A61P 1/12: Antidiarrhoeals
- A61P 1/18: for pancreatic disorders, e.g. pancreatic enzymes
- A61P 9/00: Drugs for disorders of the cardiovascular system
- A61P 11/00: Drugs for disorders of the respiratory system
- A61P 11/06: Antiasthmatics
- A61P 13/02: of urine or of the urinary tract, e.g. urine acidifiers
- A61P 13/08: of the prostate
- A61P 15/00: Drugs for genital or sexual disorders (for disorders of sex hormones A61P5/24); Contraceptives
- A61P 17/00: Drugs for dermatological disorders
- A61P 17/02: for treating wounds, ulcers, burns, scars, keloids, or the like
- A61P 19/08: for bone diseases, e.g. rachitism, Paget's disease
- A61P 25/00: Drugs for disorders of the nervous system
- A61P 27/02: Ophthalmic agents
- A61P 27/16: Otologicals
- A61P 31/00: Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P 31/04: Antibacterial agents
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C07K 7/08: having 12 to 20 amino acids (gastrins C07K14/595; somatostatins C07K14/655; melanotropins C07K14/68)
- A61K 38/00: Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00)
- Y02A 50/30: Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
- C07K: PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE

## Abstract

Beta-hairpin peptidomimetics of the general formula (I), cyclo[P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-T1-T2], and pharmaceutically acceptable salts thereof, with P1 to P12, T1 and T2 being elements as defined in the description and the claims, have Gram-negative antimicrobial activity to e.g. inhibit the growth or to kill microorganisms such as Klebsiella pneumoniae and/or Acinetobacter baumannii and/or Escherichia coli. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.

## Claims

### Claim 1

A method for the treatment of infections caused by gram-negative bacteria or for the treatment or prevention of the onset of diseases related to such infections, comprising:
administering a compound to a subject in need thereof,
wherein said infections relate to respiratory diseases or skin or soft tissue diseases or gastrointestinal diseases or eye diseases or ear diseases or CNS diseases or bone diseases or cardiovascular diseases or genitourinary diseases, or nosocomial infections, or catheter-related and non-catheter-related infections, or urinary tract infections, or bloodstream infections, and
wherein said compound is a compound of the general formula (I),
cyclo[P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-T1-T2] (I)
wherein the single elements T or P are connected in either direction from the carbonyl (C═O) point of attachment to the nitrogen (N) of the next element and wherein
T1 is DPro;
T2 is Pro; Pro((3S)OH); Pro((4S)OBn); Pic; Oic; or Tic(7OH);
P1 is Ala(CF3); Ala(2ClPhUr); Ala(4ClPhUr); Leu; Ile; Val; Nva; Trp; Phe, Tyr; Tza; or Thr;
P2 is Ala; Abu; Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser; Ser(Me); Hse; Thr; alloThr; Asp; Asn; or Gly;
P3 is Chg; Cha; tBuGly; Phe; Phe(4NH2); Phe(4F); Tyr(3F); Phe(4CF3); Tyr; Tyr(Me); or Trp;
P4 is Dab; Dab(2PyrMe); Dap; Orn; or Arg;
P5 is Lys; Orn; Orn(iPr); Dap; Dab; or Arg;
P6 is Dab; DDab; or Pip;
P7 is Dab; Dab(2PyrMe); Dap; Orn; Arg; or DDab;
P8 is Trp;
P9 is Hse; Dab; Dap; Arg; or Lys;
P10 is tBuGly; Ile; Val; Nva; Chg; Cha; Trp; Tyr; Tyr(Me); or Phg;
P11 is Ala; Ser; Ser(Me); Tza; Agp; Tyr; Dab; Thr; Asn; Asp; or DAla; and
P12 is Ser; Thr; Dap; Ala(iPrUr); Leu; or Tyr;
or a pharmaceutically acceptable salt thereof;
with the proviso that
if P2 is Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser(Me); Asp; or Asn;
then P11 is Ala; Ser; Ser(Me); Thr; Asn; Asp; or DAla.

### Claim 2

A method for disinfecting or preserving foodstuffs, cosmetics, medicaments or other nutrient-containing materials against gram-negative, comprising the step:
adding a compound to foodstuffs, cosmetics, medicaments or other nutrient-containing materials, thereby disinfecting or preserving said foodstuffs, cosmetics, medicaments or other nutrient-containing materials,
wherein said compound is a compound of the general formula (I),
cyclo[P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-T1-T2] (I)
wherein the single elements T or P are connected in either direction from the carbonyl (C═O) point of attachment to the nitrogen (N) of the next element and wherein
T1 is DPro;
T2 is Pro; Pro((3S)OH); Pro((4S)OBn); Pic; Oic; or Tic(7OH);
P1 is Ala(CF3); Ala(2ClPhUr); Ala(4ClPhUr); Leu; Ile; Val; Nva; Trp; Phe, Tyr; Tza; or Thr;
P2 is Ala; Abu; Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser; Ser(Me); Hse; Thr; alloThr; Asp; Asn; or Gly;
P3 is Chg; Cha; tBuGly; Phe; Phe(4NH2); Phe(4F); Tyr(3F); Phe(4CF3); Tyr; Tyr(Me); or Trp;
P4 is Dab; Dab(2PyrMe); Dap; Orn; or Arg;
P5 is Lys; Orn; Orn(iPr); Dap; Dab; or Arg;
P6 is Dab; DDab; or Pip;
P7 is Dab; Dab(2PyrMe); Dap; Orn; Arg; or DDab;
P8 is Trp;
P9 is Hse; Dab; Dap; Arg; or Lys;
P10 is tBuGly; Ile; Val; Nva; Chg; Cha; Trp; Tyr; Tyr(Me); or Phg;
P11 is Ala; Ser; Ser(Me); Tza; Agp; Tyr; Dab; Thr; Asn; Asp; or DAla; and
P12 is Ser; Thr; Dap; Ala(iPrUr); Leu; or Tyr;
or a pharmaceutically acceptable salt thereof;
with the proviso that
if P2 is Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser(Me); Asp; or Asn;
then P11 is Ala; Ser; Ser(Me); Thr; Asn; Asp; or DAla.

### Claim 3

A method for the manufacture of a medicament to treat infections caused by gram-negative bacteria or to treat or prevent the onset of diseases related to such infections, comprising the step:
formulating a compound with one or more physiologically acceptable carriers, diluents, excipients, or auxiliaries,
wherein said infections relate to respiratory diseases or skin or soft tissue diseases or gastrointestinal diseases or eye diseases or ear diseases or CNS diseases or bone diseases or cardiovascular diseases or genitourinary diseases, or nosocomial infections, or catheter-related and non-catheter-related infections, or urinary tract infections, or bloodstream infections;
wherein said compound is a compound of the general formula (I),
cyclo[P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-T1-T2] (I)
wherein the single elements T or P are connected in either direction from the carbonyl (C═O) point of attachment to the nitrogen (N) of the next element and wherein
T1 is DPro;
T2 is Pro; Pro((3S)OH); Pro((4S)OBn); Pic; Oic; or Tic(7OH);
P1 is Ala(CF3); Ala(2ClPhUr); Ala(4ClPhUr); Leu; Ile; Val; Nva; Trp; Phe, Tyr; Tza; or Thr;
P2 is Ala; Abu; Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser; Ser(Me); Hse; Thr; alloThr; Asp; Asn; or Gly;
P3 is Chg; Cha; tBuGly; Phe; Phe(4NH2); Phe(4F); Tyr(3F); Phe(4CF3); Tyr; Tyr(Me); or Trp;
P4 is Dab; Dab(2PyrMe); Dap; Orn; or Arg;
P5 is Lys; Orn; Orn(iPr); Dap; Dab; or Arg;
P6 is Dab; DDab; or Pip;
P7 is Dab; Dab(2PyrMe); Dap; Orn; Arg; or DDab;
P8 is Trp;
P9 is Hse; Dab; Dap; Arg; or Lys;
P10 is tBuGly; Ile; Val; Nva; Chg; Cha; Trp; Tyr; Tyr(Me); or Phg;
P11 is Ala; Ser; Ser(Me); Tza; Agp; Tyr; Dab; Thr; Asn; Asp; or DAla; and
P12 is Ser; Thr; Dap; Ala(iPrUr); Leu; or Tyr;
or a pharmaceutically acceptable salt thereof;
with the proviso that
if P2 is Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser(Me); Asp; or Asn;
then P1 is Ala; Ser; Ser(Me); Thr; Asn; Asp; or DAla.

### Claim 4

A method for the manufacture of a disinfectant or preservative against gram-negative bacteria for foodstuffs, cosmetics, medicaments and other nutrient-containing materials, comprising the step:
formulating a compound with one or more physiologically acceptable carriers, diluents, excipients, or auxiliaries,
wherein said compound is a compound of the general formula (I),
cyclo[P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-T1-T2] (I)
wherein the single elements T or P are connected in either direction from the carbonyl (C═O) point of attachment to the nitrogen (N) of the next element and wherein
T1 is DPro;
T2 is Pro; Pro((3S)OH); Pro((4S)OBn); Pic; Oic; or Tic(7OH);
P1 is Ala(CF3); Ala(2ClPhUr); Ala(4ClPhUr); Leu; Ile; Val; Nva; Trp; Phe, Tyr; Tza; or Thr;
P2 is Ala; Abu; Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser; Ser(Me); Hse; Thr; alloThr; Asp; Asn; or Gly;
P3 is Chg; Cha; tBuGly; Phe; Phe(4NH2); Phe(4F); Tyr(3F); Phe(4CF3); Tyr; Tyr(Me); or Trp;
P4 is Dab; Dab(2PyrMe); Dap; Orn; or Arg;
P5 is Lys; Orn; Orn(iPr); Dap; Dab; or Arg;
P6 is Dab; DDab; or Pip;
P7 is Dab; Dab(2PyrMe); Dap; Orn; Arg; or DDab;
P8 is Trp;
P9 is Hse; Dab; Dap; Arg; or Lys;
P10 is tBuGly; Ile; Val; Nva; Chg; Cha; Trp; Tyr; Tyr(Me); or Phg;
P11 is Ala; Ser; Ser(Me); Tza; Agp; Tyr; Dab; Thr; Asn; Asp; or DAla; and
P12 is Ser; Thr; Dap; Ala(iPrUr); Leu; or Tyr;
or a pharmaceutically acceptable salt thereof;
with the proviso that
if P2 is Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser(Me); Asp; or Asn;
then P5 is Ala; Ser; Ser(Me); Thr; Asn; Asp; or DAla.

### Claim 5

A method of treating an infection caused by gram-negative bacteria or a disease or disorder associated with an infection caused by gram-negative bacteria, comprising
administering to a subject in need thereof a pharmaceutically acceptable amount of a compound or a pharmaceutical composition,
wherein said compound is a compound of the general formula (I),
cyclo[P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-T1-T2] (I)
wherein the single elements T or P are connected in either direction from the carbonyl (C═O) point of attachment to the nitrogen (N) of the next element and wherein
T1 is DPro;
T2 is Pro; Pro((3S)OH); Pro((4S)OBn); Pic; Oic; or Tic(7OH);
P1 is Ala(CF3); Ala(2ClPhUr); Ala(4ClPhUr); Leu; Ile; Val; Nva; Trp; Phe, Tyr; Tza; or Thr;
P2 is Ala; Abu; Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser; Ser(Me); Hse; Thr; alloThr; Asp; Asn; or Gly;
P3 is Chg; Cha; tBuGly; Phe; Phe(4NH2); Phe(4F); Tyr(3F); Phe(4CF3); Tyr; Tyr(Me); or Trp;
P4 is Dab; Dab(2PyrMe); Dap; Orn; or Arg;
P5 is Lys; Orn; Orn(iPr); Dap; Dab; or Arg;
P6 is Dab; DDab; or Pip;
P7 is Dab; Dab(2PyrMe); Dap; Orn; Arg; or DDab;
P8 is Trp;
P9 is Hse; Dab; Dap; Arg; or Lys;
P10 is tBuGly; Ile; Val; Nva; Chg; Cha; Trp; Tyr; Tyr(Me); or Phg;
P11 is Ala; Ser; Ser(Me); Tza; Agp; Tyr; Dab; Thr; Asn; Asp; or DAla; and
P12 is Ser; Thr; Dap; Ala(iPrUr); Leu; or Tyr;
or a pharmaceutically acceptable salt thereof;
with the proviso that
if P2 is Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser(Me); Asp; or Asn;
then P11 is Ala; Ser; Ser(Me); Thr; Asn; Asp; or DAla;
and
wherein said composition contains said compound of the general formula (I) or a mixture of compounds of general formula (I) and at least one pharmaceutically inert carrier.

### Claim 6 (depends on 5)

The method according to claim 5, wherein said infections are selected from the group consisting of nosocomial infections, catheter-related and non-catheter-related infections, urinary tract infections, and bloodstream infections.

### Claim 7 (depends on 5)

The method according to claim 5, wherein said diseases or disorders are selected from the group consisting of ventilator-associated pneumonia (VAP), hospital-acquired pneumonia (HAP), healthcare-associated pneumonia (HCAP), cystic fibrosis, emphysema, asthma, pneumonia, epidemic diarrhea, necrotizing enterocolitis, typhlitis, gastroenteritis, pancreatitis, keratitis, endophthalmitis, otitis, brain abscess, meningitis, encephalitis, osteochondritis, pericarditis, epididymitis, prostatitis, urethritis, surgical wounds, traumatic wounds, and burns.

### Claim 8

A method for the treatment of infections caused by gram-negative bacteria or for the treatment or prevention of the onset of diseases related to such infections, comprising:
administering a composition to a subject in need thereof,
wherein said infections relate to respiratory diseases or skin or soft tissue diseases or gastrointestinal diseases or eye diseases or ear diseases or CNS diseases or bone diseases or cardiovascular diseases or genitourinary diseases, or nosocomial infections, or catheter-related and non-catheter-related infections, or urinary tract infections, or bloodstream infections,
wherein said composition contains a compound of the general formula (I) or a mixture of compounds of general formula (I) and at least one pharmaceutically inert carrier,
wherein general formula (I) is
cyclo[P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-T1-T2] (I)
wherein the single elements T or P are connected in either direction from the carbonyl (C═O) point of attachment to the nitrogen (N) of the next element and wherein
T1 is DPro;
T2 is Pro; Pro((3S)OH); Pro((4S)OBn); Pic; Oic; or Tic(7OH);
P1 is Ala(CF3); Ala(2ClPhUr); Ala(4ClPhUr); Leu; Ile; Val; Nva; Trp; Phe, Tyr; Tza; or Thr;
P2 is Ala; Abu; Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser; Ser(Me); Hse; Thr; alloThr; Asp; Asn; or Gly;
P3 is Chg; Cha; tBuGly; Phe; Phe(4NH2); Phe(4F); Tyr(3F); Phe(4CF3); Tyr; Tyr(Me); or Trp;
P4 is Dab; Dab(2PyrMe); Dap; Orn; or Arg;
P5 is Lys; Orn; Orn(iPr); Dap; Dab; or Arg;
P6 is Dab; DDab; or Pip;
P7 is Dab; Dab(2PyrMe); Dap; Orn; Arg; or DDab;
P8 is Trp;
P9 is Hse; Dab; Dap; Arg; or Lys;
P10 is tBuGly; Ile; Val; Nva; Chg; Cha; Trp; Tyr; Tyr(Me); or Phg;
P11 is Ala; Ser; Ser(Me); Tza; Agp; Tyr; Dab; Thr; Asn; Asp; or DAla; and
P12 is Ser; Thr; Dap; Ala(iPrUr); Leu; or Tyr;
or a pharmaceutically acceptable salt thereof;
with the proviso that
if P2 is Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser(Me); Asp; or Asn;
then P5 is Ala; Ser; Ser(Me); Thr; Asn; Asp; or DAla.

### Claim 9

A method for disinfecting or preserving foodstuffs, cosmetics, medicaments or other nutrient-containing materials against gram-negative bacteria, comprising the step:
adding a composition to foodstuffs, cosmetics, medicaments or other nutrient-containing materials, thereby disinfecting or preserving said foodstuffs, cosmetics, medicaments or other nutrient-containing materials,
wherein said composition contains a compound of the general formula (I) or a mixture of compounds of general formula (I) and at least one pharmaceutically inert carrier,
wherein general formula (I) is
cyclo[P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-T1-T2] (I)
wherein the single elements T or P are connected in either direction from the carbonyl (C═O) point of attachment to the nitrogen (N) of the next element and wherein
T1 is DPro;
T2 is Pro; Pro((3S)OH); Pro((4S)OBn); Pic; Oic; or Tic(7OH);
P1 is Ala(CF3); Ala(2ClPhUr); Ala(4ClPhUr); Leu; Ile; Val; Nva; Trp; Phe, Tyr; Tza; or Thr;
P2 is Ala; Abu; Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser; Ser(Me); Hse; Thr; alloThr; Asp; Asn; or Gly;
P3 is Chg; Cha; tBuGly; Phe; Phe(4NH2); Phe(4F); Tyr(3F); Phe(4CF3); Tyr; Tyr(Me); or Trp;
P4 is Dab; Dab(2PyrMe); Dap; Orn; or Arg;
P5 is Lys; Orn; Orn(iPr); Dap; Dab; or Arg;
P6 is Dab; DDab; or Pip;
P7 is Dab; Dab(2PyrMe); Dap; Orn; Arg; or DDab;
P8 is Trp;
P9 is Hse; Dab; Dap; Arg; or Lys;
P10 is tBuGly; Ile; Val; Nva; Chg; Cha; Trp; Tyr; Tyr(Me); or Phg;
P11 is Ala; Ser; Ser(Me); Tza; Agp; Tyr; Dab; Thr; Asn; Asp; or DAla; and
P12 is Ser; Thr; Dap; Ala(iPrUr); Leu; or Tyr;
or a pharmaceutically acceptable salt thereof;
with the proviso that
if P2 is Ala(2ClPhUr); Ala(3PyrMeUr); Ala(4butoxyPhUr); Ala(iPrUr); Dab(2PyrMe); Dap; Dap(2,3-OHpropionyl); Dap(AcThr); Dap(iPr); Dap(Thr); Ser(Me); Asp; or Asn;
then P5 is Ala; Ser; Ser(Me); Thr; Asn; Asp; or DAla.

### Claim 10 (depends on 1)

The method according to claim 1, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-iBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Hse-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tza-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Agp-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Dap-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Tic(7OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-Chg-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-DAla-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3 PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.

### Claim 11 (depends on 2)

The method according to claim 2, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Hse-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tza-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Agp-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Dab-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Tic(70OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dap-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-Chg-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-DAla-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3 PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.

### Claim 12 (depends on 3)

The method according to claim 3, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-Pr-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Hse-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Char-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-On-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(e)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Tic(7OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-Chg-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-DAla-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3 PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.

### Claim 13 (depends on 4)

The method according to claim 4, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Hse-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tza-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Agp-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-la-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Dab-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Tic(7OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dap-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dap-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-Chg-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.

### Claim 14 (depends on 5)

The method according to claim 5, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-D Pro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Hse-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tza-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Agp-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Dap-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S) OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Tic(7OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dap-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dap-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dap-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-On-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-Chg-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-DAla-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3 PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.

### Claim 15 (depends on 6)

The method according to claim 6, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dab(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Hse-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tza-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Agp-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-BuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Dap-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Tic(7OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dap-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-Dab-DDab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-Chg-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-DAla-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3 PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.

### Claim 16 (depends on 7)

The method according to claim 7, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-Trp-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-se-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tza-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Agp-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Dab-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-V al-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Tic(7OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dap-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dap-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Trp-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-Chg-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-DAla-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3 PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.

### Claim 17 (depends on 8)

The method according to claim 8, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Hse-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tza-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Agp-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Dab-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dap-tBuGly-Ala-Ser-DPro-Tic(7OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dap-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dap-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-Dab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab b-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Leu-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-DAla-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3 PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3 PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.

### Claim 18 (depends on 9)

The method according to claim 9, wherein the compound is selected from
cyclo(-Trp-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser(Me)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tza-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn(iPr)-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Trp-Dap(iPr)-Cha-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab(2PyrMe)-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2PyrMe)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(2,3-OHpropionyl)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(Thr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap(AcThr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Hse-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Cha-Dab-Orn-DDap-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tza-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Agp-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-Dab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr(Me)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Phe-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr(Me)-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Hse-tBuGly-Ala-Dab-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser(Me)-Ser-DPro-Oic-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Tyr-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Alb-Ser-DPro-Pro((3S)OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Tic(7 OH)—);
cyclo(-Trp-Dap-Cha-Dab-Orn-Pip-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pic-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro((4S)OBn)-);
cyclo(-Trp-Ala-Chg-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro((3S)OH)—);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Nva-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-BuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Ile-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Phe(4NH2)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-alloThr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Orn-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Val-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Arg-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Arg-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Orn-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Lys-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Arg-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr(3F)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Phe(4CF3)-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Phg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Trp-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Trp-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Tyr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asn-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Asp-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asn-Ser-DPro-Pro-);
cyclo(-Leu-Thr-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Abu-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-Chg-Ser-Thr-DPro-Pro-);
cyclo(-Ile-Ala-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Thr-Thr-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Lys-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Val-Ala-Ser-DPro-Pro-);
cyclo(-Nva-Ser-tBuGly-Dab-Orn-DDab-Dab-Trp-Dab-Cha-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Nva-Ser-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Trp-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Thr-Ser-DPro-Pro-);
cyclo(-Leu-Dap-Tyr-Dab-Dab-DDab-Dab-Trp-Dab-tBuGly-Ser-Thr-DPro-Pro-);
cyclo(-Nva-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-Chg-Ala-Ser-DPro-Pro-);
cyclo(-Ile-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Leu-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ser-Ser-DPro-Pro-);
cyclo(-Ala(CF3)-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Phe-Dap-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Tyr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-DAla-Ser-DPro-Pro-);
cyclo(-Leu-Ser-Tyr-Dab-Orn-DDab-DDab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Gly-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Dab-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Tyr-DPro-Pro-);
cyclo(-Leu-Dab-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Asp-Ser-DPro-Pro-);
cyclo(-Thr-Ser-Tyr-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Leu-DPro-Pro-);
cyclo(-Trp-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Trp-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ala(iPrUr)-DPro-Pro-);
cyclo(-Leu-Ala(2ClPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(3PyrMeUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(iPrUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Leu-Ala(4butoxyPhUr)-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(2ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
cyclo(-Ala(4ClPhUr)-Ala-Cha-Dab-Orn-DDab-Dab-Trp-Dab-tBuGly-Ala-Ser-DPro-Pro-);
or a pharmaceutically acceptable salt thereof.