# US 10,369,561 B2 · Syringe housing for pipetting a biological material, comprising integrated membranes > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,369,561 B2 - Document ID: US10369561B2 - Status: Granted - Kind: B2 - Application number: 15/535,044 - Filed: 2015-12-10 - Published: 2017-12-21 - Granted: 2019-08-06 - Earliest claimed: 2014-12-10 - Assignees: Cell.Copedia GmbH - Applicants: Cell.Copedia GmbH - Inventors: Herbert Stadler; Wilhelm Gerdes; Sabine Przibilla - Web page: https://patentgrep.com/patent/US10369561B2 ## CPC - B01L 3/0217: {of the plunger pump type} - B01L 9/54: {Supports specially adapted for pipettes and burettes} - G01N 35/1011: {Control of the position or alignment of the transfer device} - B01L 3/502: {with fluid transport, e.g. in multi-compartment structures} - B01L 2200/02: Adapting objects or devices to another - B01L 2200/023: adapted for different sizes of tubes, tips or container - B01L 2300/0609: Holders integrated in container to position an object - B01L 2300/0681: Filter - B01L 2300/0848: Specific forms of parts of containers - G01N 2035/1025: {Fluid level sensing} - B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) ## Abstract A first aspect of the invention relates to a syringe housing which can have the following elements: a syringe body which has a first open end and a second open end, a first channel being formed between the two ends; a first membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the first channel over the cross-section thereof; a syringe body attachment which has a first open end and a second open end, a second channel being formed between the two ends; a second membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the second channel over the cross-section thereof; wherein the second open end of the syringe body and the first open end of the syringe body attachment are designed so as to be connectable in a formfitting manner and thus form the syringe housing, the first channel and the second channel form a continuous channel in the connected state of the syringe housing, and the first membrane and the second membrane define an extraction volume in the region of the continuous channel. Furthermore, different embodiments provide a pipette device which is designed for the automatic use of the syringe housing according to the invention. ## Claims ### Claim 1 A syringe housing for pipetting a biological material, comprising: a syringe body which has a first open end and a second open end, a first channel being formed between the two ends; a first membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the first channel over the cross-section thereof; a syringe body attachment which has a first open end and a second open end, a second channel being formed between the two ends; a second membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the second channel over the cross-section thereof; wherein the second open end of the syringe body and the first open end of the syringe body attachment are designed so as to be connectable in a formfitting manner and thus form the syringe housing, the first channel and the second channel form a continuous channel in the connected state of the syringe housing, and the first membrane and the second membrane define an extraction volume in the region of the continuous channel. ### Claim 2 (depends on 1) The syringe housing according to claim 1, wherein the first membrane is integrally formed with the inner wall of the syringe body. ### Claim 3 (depends on 1) The syringe housing according to claim 1, wherein the diameter of the first channel in the region above the first membrane substantially corresponds to the diameter of the first channel in the region below the first membrane. ### Claim 4 (depends on 1) The syringe housing according to claim 1, wherein the transition from a region above the first membrane to a region below the first membrane is continuous. ### Claim 5 (depends on 1) The syringe housing according to claim 1, wherein the first membrane is secured to the end of the first channel. ### Claim 6 (depends on 1) The syringe housing according to claim 1, wherein the second membrane is integrally formed with the inner wall of the syringe body attachment. ### Claim 7 (depends on 1) The syringe housing according to claim 1, wherein the diameter of the second channel in the region above the second membrane substantially corresponds to the diameter of the second channel in the region below the second membrane. ### Claim 8 (depends on 1) The syringe housing according to claim 1, wherein the transition from a region above the first membrane to a region below the first membrane is continuous. ### Claim 9 (depends on 1) The syringe housing according to claim 1, wherein the first membrane is secured to the second open end of the syringe body. ### Claim 10 (depends on 1) The syringe housing according to claim 1, wherein the extraction volume has a substantially uniformly constant diameter. ### Claim 11 (depends on 1) The syringe housing according to claim 1, wherein the second open end of the syringe body and the first open end of the syringe attachment are designed to form a one-way fastening. ### Claim 12 (depends on 11) The syringe housing according to claim 11, wherein the one-way fastening is a plug-in fastening or a rotary fastening. ### Claim 13 (depends on 11) The syringe housing according to claim 11, wherein the one-way fastening has locking structures configured to prevent detaching of the syringe body from the syringe body attachment in the assembled state of the syringe housing. ### Claim 14 (depends on 1) The syringe housing according to claim 1, wherein the second open end of the syringe body and the first open end of the syringe body attachment are designed such that one of the open ends has an axially protruding collar which in the assembled state of the syringe housing engages an inwardly stepped region of the corresponding other open end. ### Claim 15 (depends on 1) The syringe housing according to claim 1, further comprising: a piston which is axially displaceably supported in the interior of the syringe housing; and preferably a piston stop configured to limit the insertion depth of the plunger in the syringe housing. ### Claim 16 (depends on 1) A pipette device comprising: a first holding device configured to receive a syringe housing according to claim 1 and to hold it in a substantially vertical position; a second holding device configured to hold and axially move a plunger inserted in said syringe housing; wherein the first holding device and the second holding device are movable relative to the pipette device. ### Claim 17 (depends on 16) The pipette device according to claim 16, further comprising: a first sensor configured to determine the distance between the first holding device and the second holding device. ### Claim 18 (depends on 16) The pipette device according to claim 16, further comprising: a second sensor configured to determine the distance between a reference point of the pipette device and the first holding device. ### Claim 19 (depends on 16) The pipette device according to claim 16, wherein the first holding device is configured as a movable base for the second holding device. ### Claim 20 (depends on 16) The pipette device according to claim 16, further comprising: a rotary plate which is arranged below the first holding device and configured to receive samples, the rotary plate being rotatable by means of a motor.