# US 10,369,396 B1 · Assembly for decontaminating and method of manufacturing the assembly > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,369,396 B1 - Document ID: US10369396B1 - Status: Granted - Kind: B1 - Application number: 16/186,059 - Filed: 2018-11-09 - Granted: 2019-08-06 - Earliest claimed: 2018-11-09 - Assignees: Battelle Memorial Institute - Applicants: Battelle Memorial Institute - Inventors: Erik W. Edwards; Steven Risser; Jeffrey Boyce - Web page: https://patentgrep.com/patent/US10369396B1 ## CPC - A62D 3/30: by reacting with chemical agents - A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)} - A61M 35/006: {using sponges, foams, absorbent pads or swabs as spreading means} - B65D 81/3266: {separated by a common rupturable seal, a clip or other removable fastening device} - A62D 2101/02: Chemical warfare substances, e.g. cholinesterase inhibitors - A62D 2101/26: containing nitrogen or phosphorus - A62D: CHEMICAL MEANS FOR EXTINGUISHING FIRES OR FOR COMBATING OR PROTECTING AGAINST HARMFUL CHEMICAL AGENTS; CHEMICAL MATERIALS FOR USE IN BREATHING APPARATUS - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - B65D: CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES ## Abstract An assembly containing a shelf-stable formulation for decontaminating skin exposed to toxic compounds located in a package formed with water and potassium bicarbonate in a first chamber; and a sponge, diacetylmonoxime (DAM), and polyethylene glycol (PEG) located in a second chamber. The package includes a barrier between the first chamber and the second chamber, with the barrier being configured to be rapidly removed when needed to enable the water and potassium bicarbonate to enter the second chamber. The package is made by placing the water and potassium bicarbonate in the first chamber of a package; mixing the DAM with PEG to form a DAM:PEG mixture; infusing the sponge with the DAM:PEG mixture to distribute DAM within the sponge; and placing the sponge, DAM and PEG in a second chamber of the package. Infusing the sponge includes solubilizing the DAM:PEG mixture in ethanol or another low boiling point solvent to form an ethanol-DAM-PEG solution and applying the ethanol-DAM-PEG solution evenly to the sponge. The ethanol is removed by applying heat and/or vacuum to the sponge. ## Claims ### Claim 1 An assembly containing a shelf-stable formulation for decontaminating skin exposed to toxic compounds comprising: a package forming a first chamber and a second chamber; water located in the first chamber; and a dry sponge and diacetylmonoxime or derivatives thereof, located in the second chamber, wherein the diacetylmonoxime is distributed within the sponge. ### Claim 2 (depends on 1) The assembly of claim 1, further comprising potassium bicarbonate in the water and polyethylene glycol distributed within the sponge. ### Claim 3 (depends on 1) The assembly of claim 1, wherein the package is formed of transparent material. ### Claim 4 (depends on 1) The assembly of claim 1, wherein the package is formed of a metallized material. ### Claim 5 (depends on 1) The assembly of claim 1, wherein package further comprises a barrier between the first chamber and second chamber that is configured to be rapidly removed to enable the water to contact the sponge. ### Claim 6 (depends on 5) The assembly of claim 5, wherein the package is made of plastic and the barrier is a thermoformed seal and the package is configured to be torn open to allow for removal of the sponge. ### Claim 7 (depends on 1) The assembly of claim 1, wherein a ratio of potassium bicarbonate to water by weight is less than 1 to 3.6. ### Claim 8 (depends on 1) The assembly of claim 1, wherein a ratio of diacetylmonoxime to polyethylene glycol to by weight ranges from about 2.25 to about 2.59. ### Claim 9 (depends on 1) The assembly of claim 1, wherein the package has a shelf life of at least 5 years at 50° C. ### Claim 10 A method of making an assembly containing a shelf-stable formulation for decontaminating skin exposed to toxic compounds, the method comprising: placing water in a first chamber of a package; and placing a sponge and diacetylmonoxime or derivatives thereof in a second chamber of the package. ### Claim 11 (depends on 10) The method of claim 10, further comprising: mixing the diacetylmonoxime with polyethylene glycol to form a diacetylmonoxime-polyethylene glycol mixture and then adding a solvent to form a solvent-diacetylmonoxime-polyethylene-glycol solution; and infusing the sponge with the solvent-diacetylmonoxime-polyethylene glycol solution to distribute diacetylmonoxime within the sponge. ### Claim 12 (depends on 10) The method of claim 10, further comprising: mixing the diacetylmonoxime or the polyethylene-glycol with a solvent and then adding the diacetylmonoxime or the polyethylene-glycol to form a solvent-diacetylmonoxime-polyethylene-glycol solution; and infusing the sponge with the solvent-diacetylmonoxime-polyethylene glycol solution to distribute diacetylmonoxime within the sponge. ### Claim 13 (depends on 10) The method of claim 10, further comprising: mixing the diacetylmonoxime with the polyethylene glycol and a solvent in any order to form a solvent-diacetylmonoxime-polyethylene-glycol solution; and infusing the sponge with the solvent-diacetylmonoxime-polyethylene glycol solution to distribute diacetylmonoxime within the sponge. ### Claim 14 (depends on 13) The method of claim 13, wherein applying the solvent-diacetylmonoxime-polyethylene glycol solution to the sponge includes dipping the sponge in the solvent-diacetylmonoxime-polyethylene glycol solution to distribute the solvent-diacetylmonoxime-polyethylene glycol solution throughout the sponge. ### Claim 15 (depends on 13) The method of claim 13, wherein applying the solvent-diacetylmonoxime-polyethylene glycol solution to the sponge includes brushing or spraying the solvent-diacetylmonoxime-polyethylene glycol solution on to the sponge. ### Claim 16 (depends on 13) The method of claim 13, wherein applying the solvent-diacetylmonoxime-polyethylene glycol solution to the sponge is conducted with a syringe or by industrial liquid dosaging. ### Claim 17 (depends on 11) The method of claim 11, wherein the solvent is ethanol, the solvent-diacetylmonoxime-polyethylene glycol solution contains ethanol and the diacetylmonoxime-polyethylene glycol mixture at a ratio of about 2.25 and the polyethylene glycol has a molar mass of 200 g/mol. ### Claim 18 (depends on 17) The method of claim 17, wherein the ethanol is anhydrous ethanol and further comprising removing the anhydrous ethanol by applying heat and/or vacuum to the sponge and adding potassium bicarbonate to the water in the first chamber. ### Claim 19 (depends on 18) The method of claim 18 further comprising verifying that the ethanol has been removed. ### Claim 20 (depends on 10) The method of claim 10 further comprising sealing the first chamber from the second chamber with a heat sealer.