# US 10,369,384 B2 · Grid calibration system for interventional procedures > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,369,384 B2 - Document ID: US10369384B2 - Status: Granted - Kind: B2 - Application number: 15/324,765 - Filed: 2015-07-09 - Published: 2017-07-20 - Granted: 2019-08-06 - Earliest claimed: 2014-07-14 - Assignees: Koninklijke Philips N.V. - Applicants: Koninklijke Philips N.V. - Inventors: Cynthia Ming-Fu Kung; Shyam Bharat - Web page: https://patentgrep.com/patent/US10369384B2 ## CPC - A61N 5/1075: {for testing, calibrating, or quality assurance of the radiation treatment apparatus} - A61B 8/12: in body cavities or body tracts, e.g. by using catheters - A61B 8/4209: {by using holders, e.g. positioning frames} - A61B 8/4263: {using sensors not mounted on the probe, e.g. mounted on an external reference frame} - A61B 34/20: Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis - A61N 5/1007: {Arrangements or means for the introduction of sources into the body} - A61N 5/1027: {Interstitial radiation therapy} - A61B 8/587: {Calibration phantoms} - A61B 2017/00274: {Prostate operation, e.g. prostatectomy, turp, bhp treatment} - A61B 2034/2051: {Electromagnetic tracking systems} - A61N 2005/1012: {Templates or grids for guiding the introduction of sources} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A grid calibration system employing interventional equipment including one or more interventional tools (23), a grid (22) having a hole matrix for supporting and guiding the interventional tool(s) (23) within a calibration area, and an imaging device (24) positioned relative to the grid (22) for generating a tool image illustrative of the interventional tool(s) (23) within the calibration area. The grid calibration system further employs a grid calibration workstation (40) for displaying any alignment adjustments to the relative positioning of the grid (22) and the imaging device (24) as derived from an image registration of the tool image and a virtual grid having a point matrix representative of the hole matrix of the grid. ## Claims ### Claim 1 A grid calibration system, comprising: interventional equipment including at least one interventional tool, a grid having a hole matrix for supporting and guiding the at least one interventional tool within a calibration area, and an imaging device positioned relative to the grid for generating a tool image that includes at least one flash point illustrative of the at least one interventional tool within the calibration area; and a grid calibration workstation in communication with the imaging device (i) to generate a grid calibration image that comprises an overlay of a virtual grid onto the tool image, wherein the virtual grid comprises a point matrix of virtual grid points representative of the hole matrix of the grid, (ii) to calculate at least one calibration adjustment to a relative positioning of the grid and the imaging device, via an image registration, that aligns the at least one flash point of the tool image and a corresponding at least one virtual grid point of the virtual grid, and (iii) to display the at least one calibration adjustment to the relative positioning of the grid and the imaging device. ### Claim 2 (depends on 1) The grid calibration system of claim 1, wherein the at least one calibration adjustment comprises an alignment adjustment that includes a horizontal adjustment of the grid relative to the imaging device. ### Claim 3 (depends on 1) The grid calibration system of claim 1, wherein the at least one calibration adjustment comprises an alignment adjustment that includes a vertical adjustment of the grid relative to the imaging device. ### Claim 4 (depends on 1) The grid calibration system of claim 1, wherein the at least one calibration adjustment comprises an alignment adjustment that includes a rotational adjustment of the imaging device relative to the grid. ### Claim 5 (depends on 1) The grid calibration system of claim 1, wherein the grid calibration workstation is further operable to display an adjustment fit error of the tool image to the virtual grid. ### Claim 6 (depends on 1) The grid calibration system of claim 1, wherein a tracking grid is representative of a tracking of at least one of (i) the grid within a tracking coordinate system and (ii) the at least one interventional tool as supported and guided by the grid within the tracking coordinate system; and wherein the grid calibration workstation is further operable to display a virtual tracking fit error of the tracking grid to the virtual grid. ### Claim 7 (depends on 1) The grid calibration system of claim 1, wherein a tracking grid is representative of a tracking of at least one of (i)the grid within a tracking coordinate system and (ii) the at least one interventional tool as supported and guided by the grid within the tracking coordinate system; and wherein the grid calibration workstation is further operable to display an image tracking fit error of the tracking grid to the tool image. ### Claim 8 (depends on 1) The grid calibration system of claim 1, wherein the grid calibration workstation is further operable to display the grid calibration image illustrating the overlay of the virtual grid onto the tool image in real-time. ### Claim 9 (depends on 8) The grid calibration system of claim 8, wherein the image registration includes: the grid calibration workstation identifying (i) the at least one flash point illustrative of the at least one interventional tool within the tool image and (ii) the corresponding at least one virtual grid point within the virtual grid; and the grid calibration workstation calculating a transformation matrix as a function of each flash point illustrative of the at least one interventional tool identified within the tool image and each virtual grid point identified within the virtual grid. ### Claim 10 (depends on 1) The grid calibration system of claim 1, wherein a tracking grid is representative of a tracking of at least one of (i) the grid within a tracking coordinate system and (ii) the at least one interventional tool as supported and guided by the grid within the tracking coordinate system; and wherein the grid calibration workstation is further operable to display the grid calibration image illustrating an overlay of the virtual grid and the tracking grid onto the tool image in real-time. ### Claim 11 (depends on 10) The grid calibration system of claim 10, wherein the image registration includes: the grid calibration workstation identifying (i)the at least one flash point illustrative of the at least one interventional tool within the tool image, (ii) the corresponding at least one virtual grid point within the virtual grid, and (iii) at least one tracking point within the tracking grid; and the grid calibration workstation calculating at least one transformation matrix as a function of each flash point illustrative of the at least one interventional tool identified within the tool image, each virtual grid point identified within the virtual grid, and each tracking point identified with the tracking grid. ### Claim 12 (depends on 1) The grid calibration system of claim 1, wherein the at least one interventional tool includes at least one catheter. ### Claim 13 (depends on 1) The grid calibration system of claim 1, wherein the at least one interventional tool includes at least one needle. ### Claim 14 (depends on 1) The grid calibration system of claim 1, wherein the hole matrix of the grid and the point matrix of the virtual grid are identical. ### Claim 15 (depends on 1) The grid calibration system of claim 1, wherein the imaging device is an ultrasound probe.