# US 10,369,285 B2 · Syringe systems and methods for multi-stage fluid delivery > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,369,285 B2 - Document ID: US10369285B2 - Status: Granted - Kind: B2 - Application number: 15/948,471 - Filed: 2018-04-09 - Published: 2018-08-09 - Granted: 2019-08-06 - Earliest claimed: 2016-06-15 - Assignees: True Concepts Medical Technologies, LLC - Applicants: True Concepts Medical Technologies, LLC - Inventors: Michael Hopkins - Web page: https://patentgrep.com/patent/US10369285B2 ## CPC - A61M 5/19: having more than one chamber - A61B 5/15003: {for venous or arterial blood} - A61B 5/150221: {Valves} - A61B 5/150236: {Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood} - A61B 5/150244: {Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood} - A61B 5/150251: {Collection chamber divided into at least two compartments, e.g. for division of samples (injection syringes having more than one chamber A61M5/19; syringes for injection of two or more media A61M5/2448, A61M5/284; sample preparation for further analysis A61B5/150755)} - A61B 5/150351: {Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel} - A61B 5/150992: {Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; Blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings or valves} - A61B 5/153: {Devices} specially adapted for taking samples of venous or arterial blood, e.g. with syringes - A61B 5/154: {Devices} using pre-evacuated means - A61M 5/284: {comprising means for injection of two or more media, e.g. by mixing} - A61M 5/31513: {Piston constructions to improve sealing or sliding} - A61M 5/3158: {the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button} - A61M 5/31596: {comprising means for injection of two or more media, e.g. by mixing} - A61M 5/32: Needles; Details of needles pertaining to their connection with syringe or hub (infusion needles A61M5/158); Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles - A61P 9/00: Drugs for disorders of the cardiovascular system - A61M 2005/1787: {Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid} - A61M 2005/3128: {Incorporating one-way valves, e.g. pressure-relief or non-return valves} - A61M 2202/04: Liquids - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS ## Abstract Embodiments of a syringe-based device for delivering fluid include a housing, a port, the port being positioned at about the distal end of the housing, a plunger assembly, the plunger assembly including, a plunger seal, a valve, and a cannula, a first fluid reservoir, where the first fluid reservoir retains a first type of fluid, a syringe including a syringe body, a syringe port, a plunger, and a second fluid reservoir, the second fluid retaining a second type of fluid, and where the syringe transitions from a first configuration in which a first portion of the first fluid type is delivered through the port, to a second configuration in which the second type of fluid in the second fluid reservoir is delivered through the port, to a third configuration in which a second portion of the first fluid type is delivered through the port. ## Claims ### Claim 1 A syringe-based method for delivering fluid, the method comprising the steps of: providing a syringe-based device comprising; (a) a housing, the housing having an open proximal end and a distal end defining an inner volume; (b) a plunger assembly, the plunger assembly having a proximal end and a distal end, wherein the plunger assembly is retained by the housing; (c) a first fluid reservoir, the first fluid reservoir being defined at least partially by the housing and the plunger assembly, wherein the first fluid reservoir is configured to retain a first amount of a first type of fluid; (d) an actuator mechanism, the actuator mechanism being selectively attachable to the plunger assembly, wherein the actuator mechanism is movable relative to the housing, the actuator mechanism comprising a syringe body; (e) a plunger being moveable within the syringe body, the plunger and the syringe body cooperating to define a second fluid reservoir, wherein the second fluid reservoir is configured to retain a second amount of a second type of fluid; and (f) a locking mechanism to selectively couple the plunger assembly and the housing; delivering a first portion of the first amount in the first fluid reservoir; delivering the second amount of the second type of fluid in the second fluid reservoir; and delivering a second portion of the first amount of the first type of fluid. ### Claim 2 (depends on 1) The method of claim 1, wherein the first type of fluid retained by the first fluid reservoir is saline. ### Claim 3 (depends on 2) The method of claim 2, wherein the first amount of the first type of fluid is from about 10 ml to about 20 ml of saline. ### Claim 4 (depends on 1) The method of claim 1, wherein the second type of fluid retained by the second fluid reservoir is a medicine. ### Claim 5 (depends on 4) The method of claim 4, wherein the medicine is epinephrine. ### Claim 6 (depends on 4) The method of claim 4, wherein the medicine is adenosine. ### Claim 7 (depends on 4) The method of claim 4, wherein the medicine is valium. ### Claim 8 (depends on 1) The method of claim 1, wherein the first amount of the first type of fluid is user selectable. ### Claim 9 (depends on 1) The method of claim 1, wherein the first fluid reservoir is selectively detachable from the second fluid reservoir. ### Claim 10 A syringe-based method for delivering fluid, the method comprising the steps of: providing a syringe-based device comprising; (a) a housing defining an inner volume, the housing comprising a port, the port being positioned at about a distal end of the housing; (b) a plunger assembly being moveable relative to the housing, the plunger assembly comprising a plunger, a plunger seal, and a valve; (c) a first fluid reservoir, the first fluid reservoir being defined at least partially by the housing and the plunger seal, wherein the first fluid reservoir contains a first amount of a first type of fluid; (d) an actuator mechanism retained at least partially within the inner volume defined by the housing, the actuator mechanism being movable relative to the housing, the actuator mechanism including a syringe body configured to be coupled to the valve; (e) a plunger moveable within the syringe body; (f) a second fluid reservoir, the second fluid reservoir being defined at least partially by the syringe body and the plunger, wherein the second fluid reservoir is configured to retain a second amount of a second type of fluid; and (g) a locking mechanism to selectively couple the plunger seal and the housing; and delivering a first portion of the first amount in the first fluid reservoir through the port; delivering the second amount of the second type of fluid in the second fluid reservoir through the port; and delivering a second portion of the first amount in the first fluid reservoir through the port. ### Claim 11 (depends on 10) The method of claim 10, wherein the first type of fluid retained by the first fluid reservoir is saline. ### Claim 12 (depends on 11) The method of claim 11, wherein the first amount of the first type of fluid is from about 10 ml to about 20 ml of saline. ### Claim 13 (depends on 10) The method of claim 10, wherein the second type of fluid retained by the second fluid reservoir is a medicine. ### Claim 14 (depends on 13) The method of claim 13, wherein the medicine is epinephrine. ### Claim 15 (depends on 13) The method of claim 13, wherein the medicine is adenosine. ### Claim 16 (depends on 13) The method of claim 13, wherein the medicine is valium. ### Claim 17 (depends on 10) The method of claim 10, wherein the first fluid reservoir is selectively detachable from the second fluid reservoir. ### Claim 18 (depends on 10) The method of claim 10, wherein the first amount in the first fluid reservoir is user selectable.