# US 10,369,090 B2 · Method of protecting teeth against erosion > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,369,090 B2 - Document ID: US10369090B2 - Status: Granted - Kind: B2 - Application number: 16/268,855 - Filed: 2019-02-06 - Published: 2019-06-06 - Granted: 2019-08-06 - Earliest claimed: 1999-11-12 - Assignees: The Procter & Gamble Company - Applicants: The Procter & Gamble Company - Inventors: Arif Ali Baig; Robert Vincent Faller; Donald James White, Jr. - Web page: https://patentgrep.com/patent/US10369090B2 ## CPC - A61K 8/21: Fluorides; Derivatives thereof - A23G 4/06: characterised by the composition {containing organic or inorganic compounds} - A23G 4/08: of the chewing gum base - A23G 4/126: {containing vitamins, antibiotics} - A61K 6/20: Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish - A61K 8/19: containing inorganic ingredients - A61K 8/20: Halogens; Compounds thereof - A61K 8/24: Phosphorous; Compounds thereof - A61K 8/25: Silicon; Compounds thereof - A61K 8/29: Titanium; Compounds thereof - A61K 8/345: {containing more than one hydroxy group} - A61K 8/365: Hydroxycarboxylic acids; Ketocarboxylic acids - A61K 8/463: {containing sulfuric acid derivatives, e.g. sodium lauryl sulfate} - A61K 8/73: Polysaccharides - A61K 8/731: {Cellulose; Quaternized cellulose derivatives} - A61K 8/81: obtained by reactions involving only carbon-to-carbon unsaturated bonds - A61K 8/8147: {Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers} - A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses - A61K 2800/28: Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants - A61K 2800/48: Thickener, Thickening system - A61K 2800/52: Stabilizers - A61K 2800/5424: anionic - A61K 2800/92: Oral administration - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A23G: COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract Disclosed are methods of treating and protecting teeth against erosion by use of oral compositions comprising polymeric mineral surface active agents, metal ions such as stannous and zinc and combinations thereof. The present methods provide improved resistance of teeth to erosive demineralization or dissolution and prevention of tooth damage by subsequent exposure of teeth to erosive chemicals such as acidic foods and beverages. ## Claims ### Claim 1 A dentifrice composition comprising: a. a metal ion source comprising stannous ions and zinc ions; b. a polyphosphate; c. a silica abrasive; d. a humectant selected from the group consisting of glycerin, sorbitol, polyethylene glycol, propylene glycol, and mixtures thereof; e. from about 0.25% to about 12%, by weight of the composition, of cocamidopropyl betaine; f. from about 0.1% to about 15%, by weight of the composition, of a thickening system comprising carboxymethylcellulose and xanthan gum; and g. from 10% to 50%, by weight of the composition, of water. ### Claim 2 (depends on 1) The dentifrice composition of claim 1, wherein the metal ion source comprises stannous fluoride. ### Claim 3 (depends on 1) The dentifrice composition of claim 1, wherein the metal ion source comprises zinc phosphate. ### Claim 4 (depends on 1) The dentifrice composition of claim 1, wherein the metal ion source comprises stannous fluoride and zinc phosphate. ### Claim 5 (depends on 4) The dentifrice composition of claim 4, wherein the metal ion source comprises about 0.454%, by weight of the composition, of stannous fluoride. ### Claim 6 (depends on 1) The dentifrice composition of claim 1, wherein the humectant comprises glycerin, sorbitol, polyethylene glycol, and propylene glycol. ### Claim 7 (depends on 1) The dentifrice composition of claim 1, wherein the dentifrice composition comprises from about 0.25% to about 12%, by weight of the composition, of sodium lauryl sulfate. ### Claim 8 (depends on 1) The dentifrice composition of claim 1, wherein the polyphosphate has two or more phosphate molecules in a linear configuration. ### Claim 9 (depends on 8) The dentifrice composition of claim 8, wherein the polyphosphate is a pyrophosphate. ### Claim 10 (depends on 1) The dentifrice composition of claim 1, wherein the dentifrice composition comprises from about 0.001% to about 5%, by weight of the composition, of a flavor system. ### Claim 11 (depends on 1) The dentifrice composition of claim 1, wherein the dentifrice composition comprises from about 0.25% to about 5%, by weight of the composition, of titanium dioxide. ### Claim 12 (depends on 1) The dentifrice composition of claim 1, wherein the dentifrice composition comprises from about 0.005% to about 5%, by weight of the composition, of a sweetening agent. ### Claim 13 A dentifrice composition comprising: a. a metal ion source comprising stannous ions and zinc ions; b. a polyphosphate; c. a silica abrasive; d. a humectant selected from the group consisting of glycerin, sorbitol, polyethylene glycol, propylene glycol, and mixtures thereof; e. from about 0.25% to about 12%, by weight of the composition, of sodium lauryl sulfate; f. from about 0.1% to about 15%, by weight of the composition, of a thickening system comprising carboxymethylcellulose and xanthan gum; and g. from 10% to 50%, by weight of the composition, of water. ### Claim 14 (depends on 13) The dentifrice composition of claim 13, wherein the metal ion source comprises stannous fluoride. ### Claim 15 (depends on 13) The dentifrice composition of claim 13, wherein the metal ion source comprises zinc phosphate. ### Claim 16 (depends on 13) The dentifrice composition of claim 13, wherein the metal ion source comprises stannous fluoride and zinc phosphate. ### Claim 17 (depends on 16) The dentifrice composition of claim 16, wherein the metal ion source comprises about 0.454%, by weight of the composition, of stannous fluoride. ### Claim 18 (depends on 13) The dentifrice composition of claim 13, wherein the humectant comprises glycerin, sorbitol, polyethylene glycol, and propylene glycol. ### Claim 19 (depends on 13) The dentifrice composition of claim 13, wherein the polyphosphate has two or more phosphate molecules in a linear configuration. ### Claim 20 (depends on 19) The dentifrice composition of claim 19, wherein the polyphosphate is a pyrophosphate. ### Claim 21 A dentifrice composition comprising: a. a metal ion source comprising stannous ions and zinc ions; b. a polyphosphate; c. a silica abrasive; d. a humectant selected from the group consisting of glycerin, sorbitol, polyethylene glycol, propylene glycol, and mixtures thereof; e. from about 0.25% to about 12%, by weight of the composition, of sodium lauryl sulfate; f. from about 0.1% to about 15%, by weight of the composition, of a thickening system selected from the group consisting of carboxyvinyl polymers, carrageenan, hydroxyethyl cellulose, sodium carboxymethylcellulose, sodium hydroxyethyl cellulose, gum karaya, xanthan gum, gum arabic, gum tragacanth, and combinations thereof; g. from 10% to 50%, by weight of the composition, of water. ### Claim 22 (depends on 21) The dentifrice composition of claim 21, wherein the metal ion source comprises stannous fluoride. ### Claim 23 (depends on 21) The dentifrice composition of claim 21, wherein the metal ion source comprises about 0.454%, by weight of the composition, of stannous fluoride. ### Claim 24 (depends on 21) The dentifrice composition of claim 21, wherein the dentifrice composition comprises from about 0.25% to about 12%, by weight of the composition, of cocamidopropyl betaine. ### Claim 25 (depends on 21) The dentifrice composition of claim 21, wherein the polyphosphate has two or more phosphate molecules in a linear configuration. ### Claim 26 (depends on 21) The dentifrice composition of claim 21, wherein the polyphosphate is tripolyphosphate. ### Claim 27 (depends on 21) The dentifrice composition of claim 21, wherein the dentifrice composition comprises from about 0.001% to about 5%, by weight of the composition, of a flavor system. ### Claim 28 (depends on 21) The dentifrice composition of claim 21, wherein the dentifrice composition comprises from about 0.005% to about 5%, by weight of the composition, of a sweetening agent.