# US 10,369,054 B2 · Varying a numerical aperture of a laser during lens fragmentation in cataract surgery

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- Number: US 10,369,054 B2
- Document ID: US10369054B2
- Status: Granted
- Kind: B2
- Application number: 15/200,768
- Filed: 2016-07-01
- Published: 2016-10-27
- Granted: 2019-08-06
- Earliest claimed: 2013-03-15
- Assignees: AMO Development, LLC
- Applicants: AMO Development, LLC
- Inventors: Anthony W. Dennison; Michael A. Campos; Hong Fu
- Web page: https://patentgrep.com/patent/US10369054B2

## CPC

- A61F 9/0084: {Laser features or special beam parameters therefor}
- A61F 9/00825: {for photodisruption}
- A61F 2009/00851: {Optical coherence topography [OCT]}
- A61F 2009/00863: {Retina}
- A61F 2009/0087: {Lens}
- A61F 2009/00887: {Cataract}
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)

## Abstract

Some embodiments disclosed here provide for a method fragmenting a cataractous lens of a patient's eye using an ultra-short pulsed laser. The method can include determining, within a lens of a patient's eye, a high NA zone where a cone angle of a laser beam with a high numerical aperture is not shadowed by the iris, and a low NA zone radially closer to the iris where the cone angle of the laser beam with a low numerical aperture is not shadowed by the iris. Laser lens fragmentation is accomplished by delivering the laser beam with the high numerical aperture to the high NA zone, and the laser beam with the low numerical aperture to the low NA zone. This can result in a more effective fragmentation of a nucleus of the lens without exposing the retina to radiation above safety standards.

## Claims

### Claim 1

A method for fragmenting a lens of a patient's eye using a surgical laser comprising:
measuring features of the patient's eye to find a total laser treatment region; determining:
a safety zone comprising a region of the patient's eye that will not receive focused laser radiation;
a high NA zone, the high numerical aperture (NA) zone comprising a region where a cone angle of a laser beam with a high numerical aperture is not shadowed by an iris of the patient's eye; and
a low NA zone, the low NA zone comprising a region radially closer to the iris than the high NA zone where a cone angle of the laser beam with a low numerical aperture is not shadowed by the iris, the low numerical aperture being lower than the high numerical aperture; and
delivering the laser beam with the high numerical aperture to the high NA zone, and delivering the laser beam with the low numerical aperture to the low NA zone without delivering the laser beam with the high numerical aperture to the low NA zone,
wherein the high NA zone, the low NA zone, and the safety zone occupy, in aggregate, approximately an entirety of the total laser treatment region.

### Claim 2 (depends on 1)

The method of claim 1, wherein the high numerical aperture is greater than or equal to 0.25.

### Claim 3 (depends on 1)

The method of claim 1, wherein the low numerical aperture is less than or equal to 0.15.

### Claim 4 (depends on 1)

The method of claim 1, wherein the measuring comprises measuring a pupil diameter.

### Claim 5 (depends on 1)

The method of claim 1, wherein the measuring comprises measuring anterior and posterior boundaries of a lens of the patient's eye.

### Claim 6 (depends on 1)

The method of claim 1, wherein the safety zone is a region of the lens of the patient's eye comprising a volume that is at least about 0.5 mm inwards from an edge of an iris of the patient's eye and at least about 0.5 mm from an anterior lens capsule and at least about 0.5 mm from a posterior lens capsule.

### Claim 7 (depends on 1)

The method of claim 1, wherein a position of the laser beam is tracked with a laser scanning system comprising a plurality of galvanometer mirrors.

### Claim 8 (depends on 1)

The method of claim 1, wherein delivering the laser beam comprises adjusting a set of lens elements to adjust a numerical aperture of the laser beam when delivery of the laser beam passes between the high NA zone and the low NA zone.