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US 10,368,759 B2Granted
Method and system for determining intracranial pressure
AssigneeLions Eye Institute Limited
InventorsDao-Yi Yu, William Morgan
Life of this patent
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Abstract
A method and apparatus for determining intracranial pressure includes a contact lens; a camera for making a plurality of images of at least one eye of a subject; one or more force transducers for controllably applying a force to the eye via the contact lens; a support system for supporting the camera, the contact lens and the one or more force transducers against the eye; and a computing device for controlling the force applied to the eye by the force transducers and stabilizing the force by negative feedback.
Claims14
A method for determining intracranial pressure (ICP) of a subject, the method comprising:
- applying force to an eye of a subject using an ophthalmodynamometer force (ODF) device to produce a plurality of intraocular pressure (IOP) values within the eye of the subject, wherein the ODF device is a video ophthalmodynamometer force device comprising a camera attached to a contact lens within a force transducer ophthalmodynamometer;
- imaging, using the camera, retinal vein and arterial pulsation of the eye of the subject by obtaining a plurality of images of the retina of the eye at the plurality of IOP values over at least one cardiac cycle;
- determining, using a computer, blood column density data by analyzing the images;
- determining, using the computer, amplitudes of blood column depth pulsation as a function of intraocular pressure (IOP) from the blood column density data;
- and
- determining, using the computer, an intracranial pressure (ICP) of the subject using the amplitude of blood column pulsation.
3 more elements
Dependencies are inferred from the claim text.