# US 10,368,736 B2 · OCT motion contrast data analysis apparatus and OCT motion contrast data analysis method

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- Number: US 10,368,736 B2
- Document ID: US10368736B2
- Status: Granted
- Kind: B2
- Application number: 15/255,461
- Filed: 2016-09-02
- Published: 2017-03-09
- Granted: 2019-08-06
- Earliest claimed: 2015-09-04
- Assignees: Nidek Co., Ltd.
- Applicants: Nidek Co., Ltd.
- Inventors: Tetsuya Kano; Ryosuke Shiba; Kazuki Okada
- Web page: https://patentgrep.com/patent/US10368736B2

## CPC

- A61B 3/0091: {Fixation targets for viewing direction}
- A61B 3/102: {for optical coherence tomography [OCT]}
- A61B 3/1025: {for confocal scanning}
- G06T 7/11: Region-based segmentation
- G06T 7/136: involving thresholding
- G06T 2207/10101: Optical tomography; Optical coherence tomography [OCT]
- G06T 2207/20092: Interactive image processing based on input by user
- G06T 2207/30041: Eye; Retina; Ophthalmic
- G06T 2207/30101: Blood vessel; Artery; Vein; Vascular
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL

## Abstract

An OCT motion contrast data analysis apparatus includes: a processor; and memory storing computer readable instructions, when executed by the processor, causing the OCT motion contrast data analysis apparatus to execute: acquiring OCT motion contrast data of a subject by an optical coherence tomography; and performing an analysis process with respect to the OCT motion contrast data based on an analysis chart set on image data different from the OCT motion contrast data.

## Claims

### Claim 1

An OCT motion contrast data analysis apparatus comprising:
a processor; and
memory storing computer readable instructions, when executed by the processor, causing the OCT motion contrast data analysis apparatus to execute:
acquiring OCT motion contrast data of a subject's eye by optical coherence tomography, wherein the OCT motion contrast data is fundus motion contrast image data of a blood vessel analysis region of the subject's eye; and
performing an analysis process with respect to the OCT motion contrast data based on an analysis chart set on image data different from the OCT motion contrast data in an extraction of blood vessels in the blood vessel analysis region.

### Claim 2 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the analysis process is associated with a change of the analysis chart and is performed based on the changed analysis chart.

### Claim 3 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the analysis processor sets a center position or a reference position of the analysis process with respect to the OCT motion contrast data based on a center position of the analysis chart.

### Claim 4 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the analysis processor performs a measurement process on the subject based on an analysis result from the analysis process.

### Claim 5 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the analysis processor sets a vascular channel analysis region based on the analysis chart, and performs a vascular channel extraction process in the set vascular channel analysis region.

### Claim 6 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the analysis processor sets a reference position of a non-vascular channel extraction process in the OCT motion contrast data based on a position of the analysis chart, and performs the non-vascular channel extraction process based on the set reference position.

### Claim 7 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the computer readable instructions, when executed by the processor, cause the OCT motion contrast data analysis apparatus to function as:
an instruction receiver configured to receive an instruction from an examiner for setting a position of the analysis chart on the image data;
wherein the analysis process is performed with respect to the OCT motion contrast data based on positional information of the analysis chart set by the instruction receiver.

### Claim 8 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the image data includes at least one of OCT data of the subject, a front image of the subject, and an analysis map related to the subject.

### Claim 9 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the image data relates to OCT data which is to be a basis of the OCT motion contrast data.

### Claim 10 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the image data is different from the OCT motion contrast data with which the analysis process is performed.

### Claim 11 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the computer readable instructions, when executed by the processor, cause the OCT motion contrast data analysis apparatus to function as an instruction receiver configured to receive an instruction from an examiner for setting a position of an analysis region or a reference position of the analysis process on the OCT motion contrast data,
wherein the analysis process is performed with respect to the OCT motion contrast data based on positional information of the analysis region or positional information of the reference position set by the instruction receiver.

### Claim 12 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein in a case of performing extraction of a blood vessel region by a threshold process, a region on the OCT motion contrast data set for calculating a threshold is set based on positional information of the analysis chart.

### Claim 13 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1, wherein the computer readable instructions, when executed by the processor, cause the OCT motion contrast data analysis apparatus to function as an instruction receiver configured to receive an instruction from an examiner for setting an analysis region on the OCT motion contrast data,
wherein an analysis region on the image data is set based on the analysis region set by the instruction receiver.

### Claim 14 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1,
wherein the subject is a fundus of the subject's eye, and
wherein at least one of a position, a range, and a shape of an analysis region which are used for performing the analysis process is set according to an acquisition region on the subject of the OCT motion contrast data.

### Claim 15 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1,
wherein the analysis chart is for measuring basis statistical amounts for measurement results of the subject in a plurality of sections which are preset.

### Claim 16 (depends on 1)

The OCT motion contrast data analysis apparatus according to claim 1,
wherein an analysis region which is set for performing the analysis process is set and divided into a plurality of sections on the OCT motion contrast data based on the analysis chart, and
wherein a arranged position and a range of each of the plurality of sections of the analysis region are set to be the same as a arranged position and a range of each of a plurality of sections of the analysis chart.

### Claim 17 (depends on 16)

The OCT motion contrast data analysis apparatus according to claim 16, wherein an analysis result of each of a plurality of sections in the analysis region and an analysis result of each a plurality of sections of the analysis chart are associated with each other and are evaluated.

### Claim 18

An OCT motion contrast data analysis method comprising:
acquiring OCT motion contrast data of a subject's eye by an optical coherence tomography, wherein the OCT motion contrast data is fundus motion contrast image data of a blood vessel analysis region of the subject's eye; and
performing an analysis process with respect to the OCT motion contrast data based on an analysis chart set on image data different from the OCT motion contrast data in an extraction of blood vessels in the blood vessel analysis region.
